3d95: Difference between revisions

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[[Image:3d95.png|left|200px]]


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==Crystal Structure of the R132K:Y134F:R111L:L121E:T54V Mutant of Apo-Cellular Retinoic Acid Binding Protein Type II at 1.20 Angstroms Resolution==
The line below this paragraph, containing "STRUCTURE_3d95", creates the "Structure Box" on the page.
<StructureSection load='3d95' size='340' side='right'caption='[[3d95]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3d95]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D95 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D95 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d95 OCA], [https://pdbe.org/3d95 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d95 RCSB], [https://www.ebi.ac.uk/pdbsum/3d95 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d95 ProSAT]</span></td></tr>
{{STRUCTURE_3d95| PDB=3d95 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/RABP2_HUMAN RABP2_HUMAN] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d9/3d95_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d95 ConSurf].
<div style="clear:both"></div>


===Crystal Structure of the R132K:Y134F:R111L:L121E:T54V Mutant of Apo-Cellular Retinoic Acid Binding Protein Type II at 1.20 Angstroms Resolution===
==See Also==
 
*[[CRABP I ( Cellular Retinoic Acid Binding Protein )|CRABP I ( Cellular Retinoic Acid Binding Protein )]]
 
*[[Cellular retinoic acid-binding protein 3D structures|Cellular retinoic acid-binding protein 3D structures]]
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*[[Gustavo Elberto Epalza Sanchez/Sandbox 1|Gustavo Elberto Epalza Sanchez/Sandbox 1]]
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*[[Molecular Playground/CRABP I (Cellular Retinoic Acid Binding Protein)|Molecular Playground/CRABP I (Cellular Retinoic Acid Binding Protein)]]
(as it appears on PubMed at http://www.pubmed.gov), where 19018099 is the PubMed ID number.
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</StructureSection>
{{ABSTRACT_PUBMED_19018099}}
 
==About this Structure==
3D95 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D95 OCA].
 
==Reference==
Structural analysis of site-directed mutants of cellular retinoic acid-binding protein II addresses the relationship between structural integrity and ligand binding., Vaezeslami S, Jia X, Vasileiou C, Borhan B, Geiger JH, Acta Crystallogr D Biol Crystallogr. 2008 Dec;64(Pt 12):1228-39. Epub 2008, Nov 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19018099 19018099]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
[[Category: Geiger JH]]
[[Category: Beta barrel]]
[[Category: Vaezeslami S]]
[[Category: Crabpii]]
[[Category: Crystallography]]
[[Category: Cytoplasm]]
[[Category: High resolution]]
[[Category: Mutant]]
[[Category: Nucleus]]
[[Category: Retinoic acid]]
[[Category: Retinoid]]
[[Category: Retinol-binding]]
[[Category: Transport]]
[[Category: Transport protein]]
[[Category: Vitamin some]]
[[Category: X-ray]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 11 20:04:37 2009''

Latest revision as of 12:40, 21 February 2024

Crystal Structure of the R132K:Y134F:R111L:L121E:T54V Mutant of Apo-Cellular Retinoic Acid Binding Protein Type II at 1.20 Angstroms ResolutionCrystal Structure of the R132K:Y134F:R111L:L121E:T54V Mutant of Apo-Cellular Retinoic Acid Binding Protein Type II at 1.20 Angstroms Resolution

Structural highlights

3d95 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RABP2_HUMAN Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3d95, resolution 1.20Å

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