1j48: Difference between revisions

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-{{Seed}}
-[[Image:1j48.png|left|200px]]
-<!--
+==Crystal Structure of Apo-C1027==
-The line below this paragraph, containing "STRUCTURE_1j48", creates the "Structure Box" on the page.
+<StructureSection load='1j48' size='340' side='right'caption='[[1j48]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1j48]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_globisporus Streptomyces globisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J48 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J48 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j48 OCA], [https://pdbe.org/1j48 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j48 RCSB], [https://www.ebi.ac.uk/pdbsum/1j48 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j48 ProSAT]</span></td></tr>
-{{STRUCTURE_1j48|  PDB=1j48  |  SCENE=  }}
+</table>
+== Function ==
-===Crystal Structure of Apo-C1027===
+[https://www.uniprot.org/uniprot/CAGA_STRGL CAGA_STRGL] Binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
-==About this Structure==
+Check<jmol>
-J48 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Streptomyces_globisporus Streptomyces globisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J48 OCA].
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j4/1j48_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j48 ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Streptomyces globisporus]]
-[[Category: Bartlam, M.]]
+[[Category: Bartlam M]]
-[[Category: Chen, Y.]]
+[[Category: Chen Y]]
-[[Category: Gao, Y.]]
+[[Category: Gao Y]]
-[[Category: Jin, L.]]
+[[Category: Jin L]]
-[[Category: Li, J.]]
+[[Category: Li J]]
-[[Category: Liu, Y.]]
+[[Category: Liu Y]]
-[[Category: Rao, Z.]]
+[[Category: Rao Z]]
-[[Category: Shao, Y.]]
+[[Category: Shao Y]]
-[[Category: Tang, H.]]
+[[Category: Tang H]]
-[[Category: Zhen, Y.]]
+[[Category: Zhen Y]]
-[[Category: Antibiotic]]
-[[Category: Dna-binding]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 10:09:07 2009''