1du0: Difference between revisions

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{{Seed}}
[[Image:1du0.png|left|200px]]


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==ENGRAILED HOMEODOMAIN Q50A VARIANT DNA COMPLEX==
The line below this paragraph, containing "STRUCTURE_1du0", creates the "Structure Box" on the page.
<StructureSection load='1du0' size='340' side='right'caption='[[1du0]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1du0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DU0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DU0 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1du0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1du0 OCA], [https://pdbe.org/1du0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1du0 RCSB], [https://www.ebi.ac.uk/pdbsum/1du0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1du0 ProSAT]</span></td></tr>
{{STRUCTURE_1du0|  PDB=1du0  |  SCENE=  }}
</table>
 
== Function ==
===ENGRAILED HOMEODOMAIN Q50A VARIANT DNA COMPLEX===
[https://www.uniprot.org/uniprot/HMEN_DROME HMEN_DROME] This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_10889025}}, adds the Publication Abstract to the page
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/du/1du0_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_10889025}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
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==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1du0 ConSurf].
1DU0 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DU0 OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:10889025</ref><references group="xtra"/>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Grant, R A.]]
[[Category: Large Structures]]
[[Category: Klemm, J D.]]
[[Category: Grant RA]]
[[Category: Pabo, C O.]]
[[Category: Klemm JD]]
[[Category: Rould, M A.]]
[[Category: Pabo CO]]
[[Category: Dna-binding protein]]
[[Category: Rould MA]]
[[Category: Homeodomain]]
[[Category: Protein-dna complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:27:32 2009''

Latest revision as of 09:59, 7 February 2024

ENGRAILED HOMEODOMAIN Q50A VARIANT DNA COMPLEXENGRAILED HOMEODOMAIN Q50A VARIANT DNA COMPLEX

Structural highlights

1du0 is a 4 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HMEN_DROME This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1du0, resolution 2.00Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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