2pkn: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-{{Seed}}
-[[Image:2pkn.png|left|200px]]
-<!--
+==Crystal structure of M tuberculosis Adenosine Kinase complexed with AMP-PCP (non-hydrolyzable ATP analog)==
-The line below this paragraph, containing "STRUCTURE_2pkn", creates the "Structure Box" on the page.
+<StructureSection load='2pkn' size='340' side='right'caption='[[2pkn]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2pkn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PKN FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene></td></tr>
-{{STRUCTURE_2pkn|  PDB=2pkn  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pkn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pkn OCA], [https://pdbe.org/2pkn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pkn RCSB], [https://www.ebi.ac.uk/pdbsum/2pkn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pkn ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ADOK_MYCTU ADOK_MYCTU] ATP dependent phosphorylation of adenosine to monophosphate derivatives (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pk/2pkn_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pkn ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of M tuberculosis Adenosine Kinase complexed with AMP-PCP (non-hydrolyzable ATP analog)===
+==See Also==
+*[[Adenosine kinase 3D structures|Adenosine kinase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_17597075}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 17597075 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_17597075}}
-==About this Structure==
-PKN is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKN OCA].
-==Reference==
-<ref group="xtra">PMID:17597075</ref><references group="xtra"/>
-[[Category: Adenosine kinase]]
 [[Category: Mycobacterium tuberculosis]]
-[[Category: Owen, J L.]]
+[[Category: Owen JL]]
-[[Category: Palaninathan, S K.]]
+[[Category: Palaninathan SK]]
-[[Category: Reddy, M C.M.]]
+[[Category: Reddy MCM]]
-[[Category: Sacchettini, J C.]]
+[[Category: Sacchettini JC]]
-[[Category: Shetty, N D.]]
+[[Category: Shetty ND]]
-[[Category: TBSGC, TB Structural Genomics Consortium.]]
+[[Category: Watson MD]]
-[[Category: Watson, M D.]]
-[[Category: Adenosine kinase]]
-[[Category: Atp]]
-[[Category: Mycobacterium tuberculosis]]
-[[Category: Structural genomic]]
-[[Category: Tb structural genomics consortium]]
-[[Category: Tbsgc]]
-[[Category: Transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:45:44 2009''