1xgw: Difference between revisions

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[[Image:1xgw.png|left|200px]]


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==The crystal structure of human enthoprotin N-terminal domain==
The line below this paragraph, containing "STRUCTURE_1xgw", creates the "Structure Box" on the page.
<StructureSection load='1xgw' size='340' side='right'caption='[[1xgw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1xgw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XGW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XGW FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xgw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xgw OCA], [https://pdbe.org/1xgw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xgw RCSB], [https://www.ebi.ac.uk/pdbsum/1xgw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xgw ProSAT]</span></td></tr>
{{STRUCTURE_1xgw| PDB=1xgw |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/EPN4_HUMAN EPN4_HUMAN] Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.<ref>PMID:12429846</ref> <ref>PMID:12538641</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xg/1xgw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xgw ConSurf].
<div style="clear:both"></div>


===The crystal structure of human enthoprotin N-terminal domain===
==See Also==
 
*[[Epsin|Epsin]]
 
== References ==
==About this Structure==
<references/>
1XGW is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XGW OCA].
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Cygler, M.]]
[[Category: Large Structures]]
[[Category: Lunin, V V.]]
[[Category: Cygler M]]
[[Category: Mazzoni, I.]]
[[Category: Lunin VV]]
[[Category: Munger, C.]]
[[Category: Mazzoni I]]
[[Category: Wagner, J.]]
[[Category: Munger C]]
[[Category: Clathrin-associated]]
[[Category: Wagner J]]
[[Category: Enth]]
[[Category: Enthoprotin]]
[[Category: Epsin-related]]
 
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