3clp: Difference between revisions

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[[Image:3clp.png|left|200px]]


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==M. loti cyclic-nucleotide binding domain mutant 2==
The line below this paragraph, containing "STRUCTURE_3clp", creates the "Structure Box" on the page.
<StructureSection load='3clp' size='340' side='right'caption='[[3clp]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3clp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesorhizobium_loti Mesorhizobium loti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CLP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CLP FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr>
{{STRUCTURE_3clp|  PDB=3clp |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3clp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3clp OCA], [https://pdbe.org/3clp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3clp RCSB], [https://www.ebi.ac.uk/pdbsum/3clp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3clp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CNGK1_RHILO CNGK1_RHILO] Cyclic nucleotide-regulated potassium channel activated by cAMP.<ref>PMID:15550244</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cl/3clp_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3clp ConSurf].
<div style="clear:both"></div>


===M. loti cyclic-nucleotide binding domain mutant 2===
==See Also==
 
*[[Ion channels 3D structures|Ion channels 3D structures]]
 
== References ==
<!--
<references/>
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__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 18619611 is the PubMed ID number.
</StructureSection>
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_18619611}}
 
==About this Structure==
3CLP is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mesorhizobium_loti Mesorhizobium loti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CLP OCA].
 
==Reference==
<ref group="xtra">PMID:18619611</ref><references group="xtra"/>
[[Category: Mesorhizobium loti]]
[[Category: Mesorhizobium loti]]
[[Category: Altieri, S L.]]
[[Category: Altieri SL]]
[[Category: Clayton, G M.]]
[[Category: Clayton GM]]
[[Category: Morais-Cabral, J H.]]
[[Category: Morais-Cabral JH]]
[[Category: Thomas, L R.]]
[[Category: Thomas LR]]
[[Category: Membrane protein]]
[[Category: Mlotik1 cyclic-nucleotide binding domain mutant 2. cyclic-amp bound]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:15:11 2009''

Latest revision as of 12:36, 21 February 2024

M. loti cyclic-nucleotide binding domain mutant 2M. loti cyclic-nucleotide binding domain mutant 2

Structural highlights

3clp is a 2 chain structure with sequence from Mesorhizobium loti. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CNGK1_RHILO Cyclic nucleotide-regulated potassium channel activated by cAMP.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Clayton GM, Silverman WR, Heginbotham L, Morais-Cabral JH. Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel. Cell. 2004 Nov 24;119(5):615-27. PMID:15550244 doi:10.1016/j.cell.2004.10.030

3clp, resolution 2.00Å

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