1xrc: Difference between revisions

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[[Image:1xrc.png|left|200px]]


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==CRYSTAL STRUCTURE OF S-ADENOSYLMETHIONINE SYNTHETASE==
The line below this paragraph, containing "STRUCTURE_1xrc", creates the "Structure Box" on the page.
<StructureSection load='1xrc' size='340' side='right'caption='[[1xrc]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1xrc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XRC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XRC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_1xrc| PDB=1xrc |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xrc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xrc OCA], [https://pdbe.org/1xrc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xrc RCSB], [https://www.ebi.ac.uk/pdbsum/1xrc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xrc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/METK_ECOLI METK_ECOLI] Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. Is essential for growth.[HAMAP-Rule:MF_00086]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xr/1xrc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xrc ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURE OF S-ADENOSYLMETHIONINE SYNTHETASE===
==See Also==
 
*[[S-adenosylmethionine synthetase 3D structures|S-adenosylmethionine synthetase 3D structures]]
 
__TOC__
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</StructureSection>
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{{ABSTRACT_PUBMED_8550549}}
 
==About this Structure==
1XRC is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XRC OCA].
 
==Reference==
<ref group="xtra">PMID:8550549</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Methionine adenosyltransferase]]
[[Category: Large Structures]]
[[Category: Kamitori, S.]]
[[Category: Kamitori S]]
[[Category: Markham, G D.]]
[[Category: Markham GD]]
[[Category: Misaki, S.]]
[[Category: Misaki S]]
[[Category: Takusagawa, F.]]
[[Category: Takusagawa F]]
[[Category: Methyltransferase]]
 
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