1i3e: Difference between revisions

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{{Seed}}
[[Image:1i3e.png|left|200px]]


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==HUMAN AZIDO-MET HEMOGLOBIN BART'S (GAMMA4)==
The line below this paragraph, containing "STRUCTURE_1i3e", creates the "Structure Box" on the page.
<StructureSection load='1i3e' size='340' side='right'caption='[[1i3e]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1i3e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I3E FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
{{STRUCTURE_1i3e| PDB=1i3e |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i3e OCA], [https://pdbe.org/1i3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i3e RCSB], [https://www.ebi.ac.uk/pdbsum/1i3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i3e ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HBG1_HUMAN HBG1_HUMAN] Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i3/1i3e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i3e ConSurf].
<div style="clear:both"></div>


===HUMAN AZIDO-MET HEMOGLOBIN BART'S (GAMMA4)===
==See Also==
 
*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11514664}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11514664 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11514664}}
 
==Disease==
Known disease associated with this structure: Fetal hemoglobin quantitative trait locus 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142200 142200]]
 
==About this Structure==
1I3E is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I3E OCA].
 
==Reference==
<ref group="xtra">PMID:11514664</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Baker, E N.]]
[[Category: Large Structures]]
[[Category: Baker, H M.]]
[[Category: Baker EN]]
[[Category: Brittain, T.]]
[[Category: Baker HM]]
[[Category: Kidd, R D.]]
[[Category: Brittain T]]
[[Category: Mathews, A J.]]
[[Category: Kidd RD]]
[[Category: Oxygen transport]]
[[Category: Mathews AJ]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 03:03:49 2009''

Latest revision as of 10:32, 7 February 2024

HUMAN AZIDO-MET HEMOGLOBIN BART'S (GAMMA4)HUMAN AZIDO-MET HEMOGLOBIN BART'S (GAMMA4)

Structural highlights

1i3e is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.86Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HBG1_HUMAN Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1i3e, resolution 1.86Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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