3thi: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(6 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:3thi.png|left|200px]]


<!--
==THIAMINASE I FROM BACILLUS THIAMINOLYTICUS==
The line below this paragraph, containing "STRUCTURE_3thi", creates the "Structure Box" on the page.
<StructureSection load='3thi' size='340' side='right'caption='[[3thi]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3thi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3THI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3THI FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3thi|  PDB=3thi |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3thi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3thi OCA], [https://pdbe.org/3thi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3thi RCSB], [https://www.ebi.ac.uk/pdbsum/3thi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3thi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/THI1_PANTH THI1_PANTH] Degrades thiamine by replacing its thiazole moiety with a wide range of nucleophiles.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/th/3thi_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3thi ConSurf].
<div style="clear:both"></div>


===THIAMINASE I FROM BACILLUS THIAMINOLYTICUS===
==See Also==
 
*[[Thiaminase|Thiaminase]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_9843405}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 9843405 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_9843405}}
 
==About this Structure==
3THI is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3THI OCA].
 
==Reference==
<ref group="xtra">PMID:9843405</ref><references group="xtra"/>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Thiamine pyridinylase]]
[[Category: Large Structures]]
[[Category: Begley, T P.]]
[[Category: Begley TP]]
[[Category: Campobasso, N.]]
[[Category: Campobasso N]]
[[Category: Ealick, S E.]]
[[Category: Ealick SE]]
[[Category: Thiamin degradation]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:56:19 2009''

Latest revision as of 16:28, 14 March 2024

THIAMINASE I FROM BACILLUS THIAMINOLYTICUSTHIAMINASE I FROM BACILLUS THIAMINOLYTICUS

Structural highlights

3thi is a 1 chain structure with sequence from Bacillus subtilis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

THI1_PANTH Degrades thiamine by replacing its thiazole moiety with a wide range of nucleophiles.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3thi, resolution 2.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=3thi&oldid=4098164"