1mxe: Difference between revisions

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{{Seed}}
[[Image:1mxe.png|left|200px]]


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==Structure of the Complex of Calmodulin with the Target Sequence of CaMKI==
The line below this paragraph, containing "STRUCTURE_1mxe", creates the "Structure Box" on the page.
<StructureSection load='1mxe' size='340' side='right'caption='[[1mxe]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mxe]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MXE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MXE FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_1mxe| PDB=1mxe |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mxe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mxe OCA], [https://pdbe.org/1mxe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mxe RCSB], [https://www.ebi.ac.uk/pdbsum/1mxe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mxe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CALM_DROME CALM_DROME] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mx/1mxe_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mxe ConSurf].
<div style="clear:both"></div>


===Structure of the Complex of Calmodulin with the Target Sequence of CaMKI===
==See Also==
 
*[[Calmodulin 3D structures|Calmodulin 3D structures]]
 
__TOC__
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</StructureSection>
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{{ABSTRACT_PUBMED_12475216}}
 
==About this Structure==
1MXE is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MXE OCA].
 
==Reference==
<ref group="xtra">PMID:12475216</ref><references group="xtra"/>
[[Category: Calcium/calmodulin-dependent protein kinase]]
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Bayley, P M.]]
[[Category: Large Structures]]
[[Category: Clapperton, J A.]]
[[Category: Rattus norvegicus]]
[[Category: Gamblin, S J.]]
[[Category: Bayley PM]]
[[Category: Martin, S R.]]
[[Category: Clapperton JA]]
[[Category: Smerdon, S J.]]
[[Category: Gamblin SJ]]
[[Category: Calmodulin]]
[[Category: Martin SR]]
[[Category: Calmodulin-pepide complex]]
[[Category: Smerdon SJ]]
[[Category: Camki]]
[[Category: Xray]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:11:05 2009''

Latest revision as of 10:49, 14 February 2024

Structure of the Complex of Calmodulin with the Target Sequence of CaMKIStructure of the Complex of Calmodulin with the Target Sequence of CaMKI

Structural highlights

1mxe is a 4 chain structure with sequence from Drosophila melanogaster and Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CALM_DROME Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1mxe, resolution 1.70Å

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