2hqg: Difference between revisions

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-{{Seed}}
-[[Image:2hqg.png|left|200px]]
-<!--
+==Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway==
-The line below this paragraph, containing "STRUCTURE_2hqg", creates the "Structure Box" on the page.
+<StructureSection load='2hqg' size='340' side='right'caption='[[2hqg]], [[Resolution|resolution]] 3.38&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2hqg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HQG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HQG FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.38&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hqg OCA], [https://pdbe.org/2hqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hqg RCSB], [https://www.ebi.ac.uk/pdbsum/2hqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hqg ProSAT]</span></td></tr>
-{{STRUCTURE_2hqg|  PDB=2hqg  |  SCENE=  }}
+</table>
+== Function ==
-===Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway===
+[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
-<!--
+Check<jmol>
-The line below this paragraph, {{ABSTRACT_PUBMED_17015668}}, adds the Publication Abstract to the page
+  <jmolCheckbox>
-(as it appears on PubMed at http://www.pubmed.gov), where 17015668 is the PubMed ID number.
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hq/2hqg_consurf.spt"</scriptWhenChecked>
--->
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-{{ABSTRACT_PUBMED_17015668}}
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
-==About this Structure==
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hqg ConSurf].
-HQG is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HQG OCA].
+<div style="clear:both"></div>
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:17015668</ref><references group="xtra"/>
+__TOC__
-[[Category: Escherichia coli]]
+</StructureSection>
-[[Category: Gu, R.]]
+[[Category: Escherichia coli K-12]]
-[[Category: Li, M.]]
+[[Category: Large Structures]]
-[[Category: McDermott, G.]]
+[[Category: Gu R]]
-[[Category: Nikaido, H.]]
+[[Category: Li M]]
-[[Category: Su, C C.]]
+[[Category: McDermott G]]
-[[Category: Takatsuka, Y.]]
+[[Category: Nikaido H]]
-[[Category: Yu, E W.]]
+[[Category: Su C-C]]
-[[Category: Membrane protein]]
+[[Category: Takatsuka Y]]
-[[Category: Multidrug efflux pump]]
+[[Category: Yu EW]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 19:56:25 2009''