2f63: Difference between revisions

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New page: left|200px<br /><applet load="2f63" size="450" color="white" frame="true" align="right" spinBox="true" caption="2f63" /> '''Solution structure of HPPK in complex with i...
 
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[[Image:2f63.gif|left|200px]]<br /><applet load="2f63" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2f63" />
'''Solution structure of HPPK in complex with inhibitor analogs AMPCPP and HP-1'''<br />


==About this Structure==
==Solution structure of HPPK in complex with inhibitor analogs AMPCPP and HP-1==
2F63 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Active as [http://en.wikipedia.org/wiki/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine_diphosphokinase 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.3 2.7.6.3] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2F63 OCA].  
<StructureSection load='2f63' size='340' side='right'caption='[[2f63]]' scene=''>
[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2f63]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F63 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f63 OCA], [https://pdbe.org/2f63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f63 RCSB], [https://www.ebi.ac.uk/pdbsum/2f63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f63 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HPPK_ECOLI HPPK_ECOLI]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/2f63_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f63 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[HPPK 3D structures|HPPK 3D structures]]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Li, G.]]
[[Category: Li G]]
[[Category: Yan, H.]]
[[Category: Yan H]]
[[Category: alpha-beta-alpha fold]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 10:23:04 2007''

Latest revision as of 21:55, 29 May 2024

Solution structure of HPPK in complex with inhibitor analogs AMPCPP and HP-1Solution structure of HPPK in complex with inhibitor analogs AMPCPP and HP-1

Structural highlights

2f63 is a 1 chain structure with sequence from Escherichia coli. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HPPK_ECOLI

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

Drag the structure with the mouse to rotate

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