2j8a: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-{{Seed}}
-[[Image:2j8a.png|left|200px]]
-<!--
+==X-ray structure of the N-terminus RRM domain of Set1==
-The line below this paragraph, containing "STRUCTURE_2j8a", creates the "Structure Box" on the page.
+<StructureSection load='2j8a' size='340' side='right'caption='[[2j8a]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2j8a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J8A FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j8a OCA], [https://pdbe.org/2j8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j8a RCSB], [https://www.ebi.ac.uk/pdbsum/2j8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j8a ProSAT]</span></td></tr>
-{{STRUCTURE_2j8a|  PDB=2j8a  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SET1_YEAST SET1_YEAST] Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.<ref>PMID:11742990</ref> <ref>PMID:11751634</ref> <ref>PMID:11752412</ref> <ref>PMID:11805083</ref> <ref>PMID:11818070</ref> <ref>PMID:12060701</ref> <ref>PMID:12353038</ref> <ref>PMID:12845608</ref> <ref>PMID:14636589</ref> <ref>PMID:15949446</ref> <ref>PMID:9398665</ref> <ref>PMID:9988274</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j8/2j8a_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2j8a ConSurf].
+<div style="clear:both"></div>
-===X-RAY STRUCTURE OF THE N-TERMINUS RRM DOMAIN OF SET1===
+==See Also==
+*[[Histone methyltransferase 3D structures|Histone methyltransferase 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-J8A is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J8A OCA].
+__TOC__
-[[Category: Histone-lysine N-methyltransferase]]
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Saccharomyces cerevisiae]]
-[[Category: Chavez, S.]]
+[[Category: Chavez S]]
-[[Category: Couprie, J.]]
+[[Category: Couprie J]]
-[[Category: Dehe, P M.]]
+[[Category: Dehe PM]]
-[[Category: Geli, V.]]
+[[Category: Geli V]]
-[[Category: Guerois, R.]]
+[[Category: Guerois R]]
-[[Category: Leulliot, N.]]
+[[Category: Leulliot N]]
-[[Category: Luciano, P.]]
+[[Category: Luciano P]]
-[[Category: Pamblanco, M.]]
+[[Category: Pamblanco M]]
-[[Category: Quevillon-Cheruel, S.]]
+[[Category: Quevillon-Cheruel S]]
-[[Category: Rodriguez-Gil, A.]]
+[[Category: Rodriguez-Gil A]]
-[[Category: Salah, P.]]
+[[Category: Salah P]]
-[[Category: Sollier, J.]]
+[[Category: Sollier J]]
-[[Category: Tilbeurgh, H Van.]]
+[[Category: Tordera V]]
-[[Category: Tordera, V.]]
+[[Category: Tresaugues L]]
-[[Category: Tresaugues, L.]]
+[[Category: Van Tilbeurgh H]]
-[[Category: Varlet, I.]]
+[[Category: Varlet I]]
-[[Category: Zinn-Justin, S.]]
+[[Category: Zinn-Justin S]]
-[[Category: Chromosomal protein]]
-[[Category: Histone methyltransferase]]
-[[Category: Methyltransferase]]
-[[Category: Nuclear protein]]
-[[Category: Rrm fold]]
-[[Category: Telomere]]
-[[Category: Transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:11:34 2009''