1kvc: Difference between revisions

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[[Image:1kvc.png|left|200px]]


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==E. COLI RIBONUCLEASE HI D134N MUTANT==
The line below this paragraph, containing "STRUCTURE_1kvc", creates the "Structure Box" on the page.
<StructureSection load='1kvc' size='340' side='right'caption='[[1kvc]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1kvc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KVC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KVC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kvc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kvc OCA], [https://pdbe.org/1kvc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kvc RCSB], [https://www.ebi.ac.uk/pdbsum/1kvc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kvc ProSAT]</span></td></tr>
{{STRUCTURE_1kvc| PDB=1kvc |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/RNH_ECOLI RNH_ECOLI] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. RNase H participates in DNA replication; it helps to specify the origin of genomic replication by suppressing initiation at origins other than the oriC locus; along with the 5'-3' exonuclease of pol1, it removes RNA primers from the Okazaki fragments of lagging strand synthesis; and it defines the origin of replication for ColE1-type plasmids by specific cleavage of an RNA preprimer.[HAMAP-Rule:MF_00042]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kv/1kvc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kvc ConSurf].
<div style="clear:both"></div>


===E. COLI RIBONUCLEASE HI D134N MUTANT===
==See Also==
 
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
__TOC__
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{{ABSTRACT_PUBMED_8931125}}
 
==About this Structure==
1KVC is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KVC OCA].
 
==Reference==
<ref group="xtra">PMID:8931125</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Ribonuclease H]]
[[Category: Large Structures]]
[[Category: Haruki, M.]]
[[Category: Haruki M]]
[[Category: Jeanteur, D.]]
[[Category: Jeanteur D]]
[[Category: Kanaya, S.]]
[[Category: Kanaya S]]
[[Category: Kashiwagi, T.]]
[[Category: Kashiwagi T]]
[[Category: Katayanagi, K.]]
[[Category: Katayanagi K]]
[[Category: Morikawa, K.]]
[[Category: Morikawa K]]
[[Category: Endoribonuclease]]
[[Category: Hydrolase]]
[[Category: Mutant]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:38:33 2009''

Latest revision as of 10:28, 14 February 2024

E. COLI RIBONUCLEASE HI D134N MUTANTE. COLI RIBONUCLEASE HI D134N MUTANT

Structural highlights

1kvc is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RNH_ECOLI Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. RNase H participates in DNA replication; it helps to specify the origin of genomic replication by suppressing initiation at origins other than the oriC locus; along with the 5'-3' exonuclease of pol1, it removes RNA primers from the Okazaki fragments of lagging strand synthesis; and it defines the origin of replication for ColE1-type plasmids by specific cleavage of an RNA preprimer.[HAMAP-Rule:MF_00042]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1kvc, resolution 1.90Å

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