1ah4: Difference between revisions

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{{Seed}}
[[Image:1ah4.png|left|200px]]


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==PIG ALDOSE REDUCTASE, HOLO FORM==
The line below this paragraph, containing "STRUCTURE_1ah4", creates the "Structure Box" on the page.
<StructureSection load='1ah4' size='340' side='right'caption='[[1ah4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ah4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AH4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AH4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AYA:N-ACETYLALANINE'>AYA</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
{{STRUCTURE_1ah4|  PDB=1ah4 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ah4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ah4 OCA], [https://pdbe.org/1ah4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ah4 RCSB], [https://www.ebi.ac.uk/pdbsum/1ah4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ah4 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ALDR_PIG ALDR_PIG] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ah/1ah4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ah4 ConSurf].
<div style="clear:both"></div>


===PIG ALDOSE REDUCTASE, HOLO FORM===
==See Also==
 
*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
 
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_9195881}}
 
==About this Structure==
1AH4 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AH4 OCA].
 
==Reference==
<ref group="xtra">PMID:9195881</ref><references group="xtra"/>
[[Category: Aldehyde reductase]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
[[Category: Moras, D.]]
[[Category: Moras D]]
[[Category: Podjarny, A.]]
[[Category: Podjarny A]]
[[Category: Aldose reductase]]
[[Category: Diabetes]]
[[Category: Inhibition]]
[[Category: Oxidoreductase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:41:01 2009''

Latest revision as of 18:24, 13 March 2024

PIG ALDOSE REDUCTASE, HOLO FORMPIG ALDOSE REDUCTASE, HOLO FORM

Structural highlights

1ah4 is a 1 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ALDR_PIG Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1ah4, resolution 2.00Å

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