2vor: Difference between revisions

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{{Seed}}
[[Image:2vor.png|left|200px]]


<!--
==Crystal Structures of Mycobacterium tuberculosis Folylpolyglutamate Synthase Complexed with ADP and AMPPCP==
The line below this paragraph, containing "STRUCTURE_2vor", creates the "Structure Box" on the page.
<StructureSection load='2vor' size='340' side='right'caption='[[2vor]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2vor]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VOR FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
{{STRUCTURE_2vor| PDB=2vor |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vor OCA], [https://pdbe.org/2vor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vor RCSB], [https://www.ebi.ac.uk/pdbsum/2vor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vor ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O53174_MYCTO O53174_MYCTO]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vo/2vor_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vor ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURES OF MYCOBACTERIUM TUBERCULOSIS FOLYLPOLYGLUTAMATE SYNTHASE COMPLEXED WITH ADP AND AMPPCP===
==See Also==
 
*[[Folylpolyglutamate synthase|Folylpolyglutamate synthase]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_18566510}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 18566510 is the PubMed ID number.
[[Category: Mycobacterium tuberculosis H37Rv]]
-->
[[Category: Baker EN]]
{{ABSTRACT_PUBMED_18566510}}
[[Category: Metcalf P]]
 
[[Category: Smith CA]]
==About this Structure==
[[Category: Young PG]]
2VOR is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOR OCA].
 
==Reference==
<ref group="xtra">PMID:18566510</ref><references group="xtra"/>
[[Category: Mycobacterium tuberculosis]]
[[Category: Tetrahydrofolate synthase]]
[[Category: Baker, E N.]]
[[Category: Metcalf, P.]]
[[Category: Smith, C A.]]
[[Category: Young, P G.]]
[[Category: Atp-binding]]
[[Category: Cell cycle]]
[[Category: Cell division]]
[[Category: Cell shape]]
[[Category: Cell wall biogenesis/degradation]]
[[Category: Cobalt binding]]
[[Category: Conformational change]]
[[Category: Folate metabolism]]
[[Category: Ligase]]
[[Category: Nucleotide binding]]
[[Category: Nucleotide-binding]]
[[Category: Peptidoglycan synthesis]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:36:01 2009''

Latest revision as of 10:07, 1 May 2024

Crystal Structures of Mycobacterium tuberculosis Folylpolyglutamate Synthase Complexed with ADP and AMPPCPCrystal Structures of Mycobacterium tuberculosis Folylpolyglutamate Synthase Complexed with ADP and AMPPCP

Structural highlights

2vor is a 1 chain structure with sequence from Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

O53174_MYCTO

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2vor, resolution 2.30Å

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