1nv8: Difference between revisions

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{{Seed}}
[[Image:1nv8.png|left|200px]]


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==N5-glutamine methyltransferase, HemK==
The line below this paragraph, containing "STRUCTURE_1nv8", creates the "Structure Box" on the page.
<StructureSection load='1nv8' size='340' side='right'caption='[[1nv8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1nv8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NV8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MEQ:N5-METHYLGLUTAMINE'>MEQ</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
{{STRUCTURE_1nv8|  PDB=1nv8  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nv8 OCA], [https://pdbe.org/1nv8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nv8 RCSB], [https://www.ebi.ac.uk/pdbsum/1nv8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nv8 ProSAT]</span></td></tr>
 
</table>
===N5-glutamine methyltransferase, HemK===
== Function ==
 
[https://www.uniprot.org/uniprot/PRMC_THEMA PRMC_THEMA] Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nv/1nv8_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12741815}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1NV8 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV8 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nv8 ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:12741815</ref><references group="xtra"/>
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: Hill, C P.]]
[[Category: Hill CP]]
[[Category: Phillips, J D.]]
[[Category: Phillips JD]]
[[Category: Schubert, H L.]]
[[Category: Schubert HL]]
[[Category: Class i adomet-dependent methyltransferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:59:36 2009''

Latest revision as of 10:59, 14 February 2024

N5-glutamine methyltransferase, HemKN5-glutamine methyltransferase, HemK

Structural highlights

1nv8 is a 2 chain structure with sequence from Thermotoga maritima. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PRMC_THEMA Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1nv8, resolution 2.20Å

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