2gf2: Difference between revisions

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[[Image:2gf2.png|left|200px]]


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==Crystal structure of human hydroxyisobutyrate dehydrogenase==
The line below this paragraph, containing "STRUCTURE_2gf2", creates the "Structure Box" on the page.
<StructureSection load='2gf2' size='340' side='right'caption='[[2gf2]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2gf2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GF2 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.38&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf2 OCA], [https://pdbe.org/2gf2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gf2 RCSB], [https://www.ebi.ac.uk/pdbsum/2gf2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gf2 ProSAT]</span></td></tr>
{{STRUCTURE_2gf2|  PDB=2gf2  |  SCENE=  }}
</table>
 
== Function ==
===Crystal structure of human hydroxyisobutyrate dehydrogenase===
[https://www.uniprot.org/uniprot/3HIDH_HUMAN 3HIDH_HUMAN]
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
2GF2 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF2 OCA].  
  <jmolCheckbox>
[[Category: 3-hydroxyisobutyrate dehydrogenase]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gf/2gf2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gf2 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Burgess, N.]]
[[Category: Arrowsmith CH]]
[[Category: Delft, F von.]]
[[Category: Burgess N]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Gileadi, O.]]
[[Category: Gileadi O]]
[[Category: Gorrec, F.]]
[[Category: Gorrec F]]
[[Category: Oppermann, U.]]
[[Category: Oppermann U]]
[[Category: Papagrigoriou, E.]]
[[Category: Papagrigoriou E]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Salah E]]
[[Category: Salah, E.]]
[[Category: Smee C]]
[[Category: Smee, C.]]
[[Category: Sundstrom M]]
[[Category: Sundstrom, M.]]
[[Category: Turnbull AP]]
[[Category: Turnbull, A P.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Von Delft F]]
[[Category: Dehydrogenase]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
 
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