1xxc: Difference between revisions

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[[Image:1xxc.png|left|200px]]


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==C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR==
The line below this paragraph, containing "STRUCTURE_1xxc", creates the "Structure Box" on the page.
<StructureSection load='1xxc' size='340' side='right'caption='[[1xxc]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1xxc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XXC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xxc OCA], [https://pdbe.org/1xxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xxc RCSB], [https://www.ebi.ac.uk/pdbsum/1xxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xxc ProSAT]</span></td></tr>
{{STRUCTURE_1xxc| PDB=1xxc |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/ARGR_ECOLI ARGR_ECOLI] Negatively controls the expression of the four operons of arginine biosynthesis in addition to the carAB operon. Predominantly interacts with A/T residues in ARG boxes. It also binds to a specific site in cer locus. Thus it is essential for cer-mediated site-specific recombination in ColE1. It is necessary for monomerization of the plasmid ColE1.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xx/1xxc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xxc ConSurf].
<div style="clear:both"></div>


===C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR===
==See Also==
 
*[[Arginine repressor 3D structures|Arginine repressor 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_8594204}}, adds the Publication Abstract to the page
[[Category: Escherichia coli K-12]]
(as it appears on PubMed at http://www.pubmed.gov), where 8594204 is the PubMed ID number.
[[Category: Large Structures]]
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[[Category: Ghosh G]]
{{ABSTRACT_PUBMED_8594204}}
[[Category: Maas WK]]
 
[[Category: Sigler PB]]
==About this Structure==
[[Category: Van Duyne GD]]
1XXC is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXC OCA].
 
==Reference==
<ref group="xtra">PMID:8594204</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Duyne, G D.Van.]]
[[Category: Ghosh, G.]]
[[Category: Maas, W K.]]
[[Category: Sigler, P B.]]
[[Category: Dna binding regulatory protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:59:36 2009''

Latest revision as of 11:53, 14 February 2024

C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSORC-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR

Structural highlights

1xxc is a 6 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.8Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ARGR_ECOLI Negatively controls the expression of the four operons of arginine biosynthesis in addition to the carAB operon. Predominantly interacts with A/T residues in ARG boxes. It also binds to a specific site in cer locus. Thus it is essential for cer-mediated site-specific recombination in ColE1. It is necessary for monomerization of the plasmid ColE1.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1xxc, resolution 2.80Å

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