1hjp: Difference between revisions

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[[Image:1hjp.png|left|200px]]


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==HOLLIDAY JUNCTION BINDING PROTEIN RUVA FROM E. COLI==
The line below this paragraph, containing "STRUCTURE_1hjp", creates the "Structure Box" on the page.
<StructureSection load='1hjp' size='340' side='right'caption='[[1hjp]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1hjp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HJP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HJP FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hjp OCA], [https://pdbe.org/1hjp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hjp RCSB], [https://www.ebi.ac.uk/pdbsum/1hjp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hjp ProSAT]</span></td></tr>
{{STRUCTURE_1hjp| PDB=1hjp |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/RUVA_ECOLI RUVA_ECOLI] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Binds both single- and double-stranded DNA (dsDNA). Binds preferentially to supercoiled rather than to relaxed dsDNA.<ref>PMID:8433990</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hj/1hjp_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hjp ConSurf].
<div style="clear:both"></div>


===HOLLIDAY JUNCTION BINDING PROTEIN RUVA FROM E. COLI===
==See Also==
 
*[[Helicase 3D structures|Helicase 3D structures]]
 
== References ==
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{{ABSTRACT_PUBMED_9493263}}
 
==About this Structure==
1HJP is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HJP OCA].
 
==Reference==
<ref group="xtra">PMID:9493263</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Ariyoshi, M.]]
[[Category: Large Structures]]
[[Category: Iwasaki, H.]]
[[Category: Ariyoshi M]]
[[Category: Morikawa, K.]]
[[Category: Iwasaki H]]
[[Category: Nishino, T.]]
[[Category: Morikawa K]]
[[Category: Shinagawa, H.]]
[[Category: Nishino T]]
[[Category: Dna recombination]]
[[Category: Shinagawa H]]
[[Category: Dna repair]]
[[Category: Holliday junction binding]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:08:50 2009''

Latest revision as of 10:28, 7 February 2024

HOLLIDAY JUNCTION BINDING PROTEIN RUVA FROM E. COLIHOLLIDAY JUNCTION BINDING PROTEIN RUVA FROM E. COLI

Structural highlights

1hjp is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.5Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RUVA_ECOLI The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Binds both single- and double-stranded DNA (dsDNA). Binds preferentially to supercoiled rather than to relaxed dsDNA.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Tsaneva IR, Muller B, West SC. RuvA and RuvB proteins of Escherichia coli exhibit DNA helicase activity in vitro. Proc Natl Acad Sci U S A. 1993 Feb 15;90(4):1315-9. PMID:8433990

1hjp, resolution 2.50Å

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