1lc3: Difference between revisions

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OCA

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-{{Seed}}
-[[Image:1lc3.png|left|200px]]
-<!--
+==Crystal Structure of a Biliverdin Reductase Enzyme-Cofactor Complex==
-The line below this paragraph, containing "STRUCTURE_1lc3", creates the "Structure Box" on the page.
+<StructureSection load='1lc3' size='340' side='right'caption='[[1lc3]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1lc3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LC3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LC3 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-{{STRUCTURE_1lc3|  PDB=1lc3  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lc3 OCA], [https://pdbe.org/1lc3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lc3 RCSB], [https://www.ebi.ac.uk/pdbsum/1lc3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lc3 ProSAT]</span></td></tr>
+</table>
-===Crystal Structure of a Biliverdin Reductase Enzyme-Cofactor Complex===
+== Function ==
+[https://www.uniprot.org/uniprot/BIEA_RAT BIEA_RAT] Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_12079357}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 12079357 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lc/1lc3_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_12079357}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-LC3 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LC3 OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lc3 ConSurf].
+<div style="clear:both"></div>
-==Reference==
+__TOC__
-<ref group="xtra">PMID:12079357</ref><references group="xtra"/>
+</StructureSection>
-[[Category: Biliverdin reductase]]
+[[Category: Large Structures]]
 [[Category: Rattus norvegicus]]
-[[Category: Hill, C P.]]
+[[Category: Hill CP]]
-[[Category: Maines, M D.]]
+[[Category: Maines MD]]
-[[Category: McCoubrey, W.]]
+[[Category: McCoubrey W]]
-[[Category: Phillips, J D.]]
+[[Category: Phillips JD]]
-[[Category: Whitby, F G.]]
+[[Category: Whitby FG]]
-[[Category: Bile pigment]]
-[[Category: Bilirubin]]
-[[Category: Biliverdin reductase]]
-[[Category: Heme]]
-[[Category: Nadh]]
-[[Category: Tetrapyrrole]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:33:27 2009''