1nd4: Difference between revisions

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[[Image:1nd4.png|left|200px]]


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==Crystal structure of aminoglycoside-3'-phosphotransferase-IIa==
The line below this paragraph, containing "STRUCTURE_1nd4", creates the "Structure Box" on the page.
<StructureSection load='1nd4' size='340' side='right'caption='[[1nd4]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1nd4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ND4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ND4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
{{STRUCTURE_1nd4| PDB=1nd4 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nd4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nd4 OCA], [https://pdbe.org/1nd4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nd4 RCSB], [https://www.ebi.ac.uk/pdbsum/1nd4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nd4 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KKA2_KLEPN KKA2_KLEPN] Resistance to kanamycin, neomycin, paromomycin, ribostamycin, butirosin and gentamicin B.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nd/1nd4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nd4 ConSurf].
<div style="clear:both"></div>


===Crystal structure of aminoglycoside-3'-phosphotransferase-IIa===
==See Also==
 
*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
 
__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 12628253 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12628253}}
 
==About this Structure==
1ND4 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ND4 OCA].
 
==Reference==
<ref group="xtra">PMID:12628253</ref><references group="xtra"/>
[[Category: Kanamycin kinase]]
[[Category: Klebsiella pneumoniae]]
[[Category: Klebsiella pneumoniae]]
[[Category: Baker, E N.]]
[[Category: Large Structures]]
[[Category: Nurizzo, D.]]
[[Category: Baker EN]]
[[Category: Shewry, S C.]]
[[Category: Nurizzo D]]
[[Category: Smith, C A.]]
[[Category: Shewry SC]]
[[Category: Atpase]]
[[Category: Smith CA]]
[[Category: Kanamycin]]
[[Category: Phosphotransferase]]
[[Category: Protein kinase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:13:25 2009''

Latest revision as of 16:27, 13 March 2024

Crystal structure of aminoglycoside-3'-phosphotransferase-IIaCrystal structure of aminoglycoside-3'-phosphotransferase-IIa

Structural highlights

1nd4 is a 2 chain structure with sequence from Klebsiella pneumoniae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KKA2_KLEPN Resistance to kanamycin, neomycin, paromomycin, ribostamycin, butirosin and gentamicin B.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1nd4, resolution 2.10Å

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OCA
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