2deb: Difference between revisions

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{{Seed}}
[[Image:2deb.png|left|200px]]


<!--
==Crystal structure of rat carnitine palmitoyltransferase 2 in space group C2221==
The line below this paragraph, containing "STRUCTURE_2deb", creates the "Structure Box" on the page.
<StructureSection load='2deb' size='340' side='right'caption='[[2deb]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2deb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DEB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
{{STRUCTURE_2deb|  PDB=2deb  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2deb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2deb OCA], [https://pdbe.org/2deb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2deb RCSB], [https://www.ebi.ac.uk/pdbsum/2deb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2deb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CPT2_RAT CPT2_RAT]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/de/2deb_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2deb ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system that imports fatty acids into mitochondria. The crystal structure of rat CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic insert mediating membrane association.


===Crystal structure of rat carnitine palmitoyltransferase 2 in space group C2221===
A monotopic membrane protein goes solo.,Mattevi A Structure. 2006 Apr;14(4):628-9. PMID:16615901<ref>PMID:16615901</ref>


From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2deb" style="background-color:#fffaf0;"></div>


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==See Also==
The line below this paragraph, {{ABSTRACT_PUBMED_16615901}}, adds the Publication Abstract to the page
*[[Carnitine palmitoyltransferase|Carnitine palmitoyltransferase]]
(as it appears on PubMed at http://www.pubmed.gov), where 16615901 is the PubMed ID number.
== References ==
-->
<references/>
{{ABSTRACT_PUBMED_16615901}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
2DEB is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEB OCA].
 
==Reference==
<ref group="xtra">PMID:16615901</ref><references group="xtra"/>
[[Category: Carnitine O-palmitoyltransferase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Banner, D W.]]
[[Category: Banner DW]]
[[Category: Benz, J.]]
[[Category: Benz J]]
[[Category: Chomienne, O.]]
[[Category: Chomienne O]]
[[Category: Gsell, B.]]
[[Category: De Roo E]]
[[Category: Hennig, M.]]
[[Category: Gsell B]]
[[Category: Mueller, F.]]
[[Category: Hennig M]]
[[Category: Roo, E De.]]
[[Category: Mueller F]]
[[Category: Rufer, A C.]]
[[Category: Rufer AC]]
[[Category: Stihle, M.]]
[[Category: Stihle M]]
[[Category: Thoma, R.]]
[[Category: Thoma R]]
[[Category: Central six-stranded beta-sheet]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:12:05 2009''

Latest revision as of 10:55, 30 October 2024

Crystal structure of rat carnitine palmitoyltransferase 2 in space group C2221Crystal structure of rat carnitine palmitoyltransferase 2 in space group C2221

Structural highlights

2deb is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.6Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CPT2_RAT

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system that imports fatty acids into mitochondria. The crystal structure of rat CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic insert mediating membrane association.

A monotopic membrane protein goes solo.,Mattevi A Structure. 2006 Apr;14(4):628-9. PMID:16615901[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

See Also

References

  1. ↑ Mattevi A. A monotopic membrane protein goes solo. Structure. 2006 Apr;14(4):628-9. PMID:16615901 doi:10.1016/j.str.2006.03.002

2deb, resolution 1.60Å

Drag the structure with the mouse to rotate

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