2izx: Difference between revisions

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-{{Seed}}
-[[Image:2izx.png|left|200px]]
-<!--
+==Molecular Basis of AKAP Specificity for PKA Regulatory Subunits==
-The line below this paragraph, containing "STRUCTURE_2izx", creates the "Structure Box" on the page.
+<StructureSection load='2izx' size='340' side='right'caption='[[2izx]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2izx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IZX FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTD:DITHIANE+DIOL'>DTD</scene></td></tr>
-{{STRUCTURE_2izx|  PDB=2izx  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2izx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izx OCA], [https://pdbe.org/2izx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2izx RCSB], [https://www.ebi.ac.uk/pdbsum/2izx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2izx ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/KAP2_HUMAN KAP2_HUMAN] Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iz/2izx_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2izx ConSurf].
+<div style="clear:both"></div>
-===MOLECULAR BASIS OF AKAP SPECIFICITY FOR PKA REGULATORY SUBUNITS===
+==See Also==
+*[[CAMP-dependent protein kinase 3D structures|CAMP-dependent protein kinase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_17081989}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 17081989 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_17081989}}
-==About this Structure==
-IZX is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZX OCA].
-==Reference==
-<ref group="xtra">PMID:17081989</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: CAMP-dependent protein kinase]]
+[[Category: Large Structures]]
-[[Category: Barford, D.]]
+[[Category: Synthetic construct]]
-[[Category: Carlson, C R.]]
+[[Category: Barford D]]
-[[Category: Dokurno, P.]]
+[[Category: Carlson CR]]
-[[Category: Gold, M G.]]
+[[Category: Dokurno P]]
-[[Category: Hoshi, N.]]
+[[Category: Gold MG]]
-[[Category: Lygren, B.]]
+[[Category: Hoshi N]]
-[[Category: Mcconnachie, G.]]
+[[Category: Lygren B]]
-[[Category: Scott, J D.]]
+[[Category: McConnachie G]]
-[[Category: Tasken, K.]]
+[[Category: Scott JD]]
-[[Category: Acetylation]]
+[[Category: Tasken K]]
-[[Category: Akap]]
-[[Category: Anchor]]
-[[Category: Camp]]
-[[Category: Camp-binding]]
-[[Category: Kinase]]
-[[Category: Nucleotide-binding]]
-[[Category: Phosphorylation]]
-[[Category: Pka]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:55:05 2009''