2ioa: Difference between revisions

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OCA

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-{{Seed}}
-[[Image:2ioa.png|left|200px]]
-<!--
+==E. coli Bifunctional glutathionylspermidine synthetase/amidase Incomplex with Mg2+ and ADP and phosphinate inhibitor==
-The line below this paragraph, containing "STRUCTURE_2ioa", creates the "Structure Box" on the page.
+<StructureSection load='2ioa' size='340' side='right'caption='[[2ioa]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2ioa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IOA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IOA FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=GGA:D-GAMMA-GLUTAMYL-N-{[(R)-{4-[(4-AMINOBUTYL)AMINO]BUTYL}(PHOSPHONOOXY)PHOSPHORYL]METHYL}-D-ALANINAMIDE'>GGA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-{{STRUCTURE_2ioa|  PDB=2ioa  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ioa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ioa OCA], [https://pdbe.org/2ioa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ioa RCSB], [https://www.ebi.ac.uk/pdbsum/2ioa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ioa ProSAT]</span></td></tr>
+</table>
-===E. coli Bifunctional glutathionylspermidine synthetase/amidase Incomplex with Mg2+ and ADP and phosphinate inhibitor===
+== Function ==
+[https://www.uniprot.org/uniprot/GSP_ECOLI GSP_ECOLI] Catalyzes the formation of an amide bond between glutathione and spermidine coupled with hydrolysis of ATP; also catalyzes the hydrolysis of glutathionylspermidine to glutathione and spermidine.
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_17124497}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 17124497 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/io/2ioa_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_17124497}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-IOA is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IOA OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ioa ConSurf].
+<div style="clear:both"></div>
-==Reference==
+__TOC__
-<ref group="xtra">PMID:17124497</ref><references group="xtra"/>
+</StructureSection>
 [[Category: Escherichia coli]]
-[[Category: Chiang, B Y.]]
+[[Category: Large Structures]]
-[[Category: Chong, C M.]]
+[[Category: Chiang BY]]
-[[Category: Chou, C C.]]
+[[Category: Chong CM]]
-[[Category: Coward, J K.]]
+[[Category: Chou CC]]
-[[Category: Ko, T P.]]
+[[Category: Coward JK]]
-[[Category: Lin, C H.]]
+[[Category: Ko TP]]
-[[Category: Pai, C H.]]
+[[Category: Lin CH]]
-[[Category: Wang, A H.J.]]
+[[Category: Pai CH]]
-[[Category: Yen, F J.]]
+[[Category: Wang AH-J]]
-[[Category: Bifunctional glutathionylspermidine synthetase/amidase]]
+[[Category: Yen FJ]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:51:56 2009''