1qtw: Difference between revisions

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-{{Seed}}
-[[Image:1qtw.png|left|200px]]
-<!--
+==HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI DNA REPAIR ENZYME ENDONUCLEASE IV==
-The line below this paragraph, containing "STRUCTURE_1qtw", creates the "Structure Box" on the page.
+<StructureSection load='1qtw' size='340' side='right'caption='[[1qtw]], [[Resolution|resolution]] 1.02&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1qtw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QTW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QTW FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.02&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_1qtw|  PDB=1qtw  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qtw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qtw OCA], [https://pdbe.org/1qtw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qtw RCSB], [https://www.ebi.ac.uk/pdbsum/1qtw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qtw ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/END4_ECOLI END4_ECOLI] Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qt/1qtw_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qtw ConSurf].
+<div style="clear:both"></div>
-===HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI DNA REPAIR ENZYME ENDONUCLEASE IV===
+==See Also==
+*[[Endonuclease 3D structures|Endonuclease 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_10458614}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 10458614 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_10458614}}
-==About this Structure==
-QTW is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QTW OCA].
-==Reference==
-<ref group="xtra">PMID:10458614</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Cunningham, R P.]]
+[[Category: Large Structures]]
-[[Category: Guan, Y.]]
+[[Category: Cunningham RP]]
-[[Category: Haas, B J.]]
+[[Category: Guan Y]]
-[[Category: Hosfield, D J.]]
+[[Category: Haas BJ]]
-[[Category: Tainer, J A.]]
+[[Category: Hosfield DJ]]
-[[Category: Dna repair enzyme]]
+[[Category: Tainer JA]]
-[[Category: Tim barrel]]
-[[Category: Trinuclear zn cluster]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:45:02 2009''