2pu5: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:2pu5.png|left|200px]]


<!--
==Crystal Structure of a C-C bond hydrolase, BphD, from Burkholderia xenovorans LB400==
The line below this paragraph, containing "STRUCTURE_2pu5", creates the "Structure Box" on the page.
<StructureSection load='2pu5' size='340' side='right'caption='[[2pu5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2pu5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Paraburkholderia_xenovorans_LB400 Paraburkholderia xenovorans LB400]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PU5 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
{{STRUCTURE_2pu5|  PDB=2pu5  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pu5 OCA], [https://pdbe.org/2pu5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pu5 RCSB], [https://www.ebi.ac.uk/pdbsum/2pu5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pu5 ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of a C-C bond hydrolase, BphD, from Burkholderia xenovorans LB400===
== Function ==
 
[https://www.uniprot.org/uniprot/BPHD_PARXL BPHD_PARXL] Catalyzes an unusual C-C bond hydrolysis of 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid (HOPDA) to produce benzoic acid and 2-hydroxy-2,4-pentadienoic acid (HPD).<ref>PMID:16964968</ref>
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_17442675}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 17442675 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pu/2pu5_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_17442675}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2PU5 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Burkholderia_xenovorans Burkholderia xenovorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PU5 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pu5 ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
<ref group="xtra">PMID:17442675</ref><references group="xtra"/>
<references/>
[[Category: Burkholderia xenovorans]]
__TOC__
[[Category: Bhowmik, S.]]
</StructureSection>
[[Category: Bolin, J T.]]
[[Category: Large Structures]]
[[Category: C-c bond hydrolase]]
[[Category: Paraburkholderia xenovorans LB400]]
 
[[Category: Bhowmik S]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:17:33 2009''
[[Category: Bolin JT]]

Latest revision as of 12:11, 21 February 2024

Crystal Structure of a C-C bond hydrolase, BphD, from Burkholderia xenovorans LB400Crystal Structure of a C-C bond hydrolase, BphD, from Burkholderia xenovorans LB400

Structural highlights

2pu5 is a 2 chain structure with sequence from Paraburkholderia xenovorans LB400. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

BPHD_PARXL Catalyzes an unusual C-C bond hydrolysis of 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid (HOPDA) to produce benzoic acid and 2-hydroxy-2,4-pentadienoic acid (HPD).[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Horsman GP, Ke J, Dai S, Seah SY, Bolin JT, Eltis LD. Kinetic and structural insight into the mechanism of BphD, a C-C bond hydrolase from the biphenyl degradation pathway. Biochemistry. 2006 Sep 19;45(37):11071-86. PMID:16964968 doi:10.1021/bi0611098

2pu5, resolution 2.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=2pu5&oldid=4062527"