2qnc: Difference between revisions

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[[Image:2qnc.png|left|200px]]


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==Crystal structure of T4 Endonuclease VII N62D mutant in complex with a DNA Holliday junction==
The line below this paragraph, containing "STRUCTURE_2qnc", creates the "Structure Box" on the page.
<StructureSection load='2qnc' size='340' side='right'caption='[[2qnc]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2qnc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QNC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QNC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_2qnc| PDB=2qnc |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qnc OCA], [https://pdbe.org/2qnc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qnc RCSB], [https://www.ebi.ac.uk/pdbsum/2qnc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qnc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/END7_BPT4 END7_BPT4] Cleaves DNA cruciform and Y-structures as well as heteroduplex loops. Resolves Holliday junctions, recognizes a broad spectrum of DNA substrates ranging from branched DNAs to single base mismatches.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qn/2qnc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qnc ConSurf].
<div style="clear:both"></div>


===Crystal structure of T4 Endonuclease VII N62D mutant in complex with a DNA Holliday junction===
==See Also==
 
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_17873859}}, adds the Publication Abstract to the page
[[Category: Escherichia virus T4]]
(as it appears on PubMed at http://www.pubmed.gov), where 17873859 is the PubMed ID number.
[[Category: Large Structures]]
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[[Category: Biertumpfel C]]
{{ABSTRACT_PUBMED_17873859}}
[[Category: Suck D]]
 
[[Category: Yang W]]
==About this Structure==
2QNC is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QNC OCA].
 
==Reference==
<ref group="xtra">PMID:17873859</ref><references group="xtra"/>
[[Category: Crossover junction endodeoxyribonuclease]]
[[Category: Enterobacteria phage t4]]
[[Category: Biertumpfel, C.]]
[[Category: Suck, D.]]
[[Category: Yang, W.]]
[[Category: Alternative initiation]]
[[Category: Calcium]]
[[Category: Endo vii]]
[[Category: Four-way junction]]
[[Category: Holliday junction]]
[[Category: Hydrolase]]
[[Category: Hydrolase/dna complex]]
[[Category: Metal-binding]]
[[Category: Resolvase]]
[[Category: Resolving-enzyme]]
[[Category: T4 endonuclease vii]]
[[Category: Zinc]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:38:16 2009''

Latest revision as of 12:17, 21 February 2024

Crystal structure of T4 Endonuclease VII N62D mutant in complex with a DNA Holliday junctionCrystal structure of T4 Endonuclease VII N62D mutant in complex with a DNA Holliday junction

Structural highlights

2qnc is a 6 chain structure with sequence from Escherichia virus T4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.1Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

END7_BPT4 Cleaves DNA cruciform and Y-structures as well as heteroduplex loops. Resolves Holliday junctions, recognizes a broad spectrum of DNA substrates ranging from branched DNAs to single base mismatches.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2qnc, resolution 3.10Å

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