2i05: Difference between revisions

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[[Image:2i05.png|left|200px]]


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==Escherichia Coli Replication Terminator Protein (Tus) Complexed With TerA DNA==
The line below this paragraph, containing "STRUCTURE_2i05", creates the "Structure Box" on the page.
<StructureSection load='2i05' size='340' side='right'caption='[[2i05]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2i05]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I05 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
{{STRUCTURE_2i05| PDB=2i05 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i05 OCA], [https://pdbe.org/2i05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i05 RCSB], [https://www.ebi.ac.uk/pdbsum/2i05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i05 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TUS_ECOLI TUS_ECOLI] Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i0/2i05_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i05 ConSurf].
<div style="clear:both"></div>


===Escherichia Coli Replication Terminator Protein (Tus) Complexed With TerA DNA===
==See Also==
 
*[[Replication Termination Protein|Replication Termination Protein]]
 
__TOC__
==About this Structure==
</StructureSection>
2I05 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I05 OCA].
 
==Reference==
<ref group="xtra">PMID:16814717</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Dixon, N E.]]
[[Category: Large Structures]]
[[Category: Mulcair, M D.]]
[[Category: Dixon NE]]
[[Category: Oakley, A J.]]
[[Category: Mulcair MD]]
[[Category: Schaeffer, P M.]]
[[Category: Oakley AJ]]
[[Category: Protein-dna complex]]
[[Category: Schaeffer PM]]
[[Category: Replication/dna complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:01:02 2009''

Latest revision as of 11:52, 25 October 2023

Escherichia Coli Replication Terminator Protein (Tus) Complexed With TerA DNAEscherichia Coli Replication Terminator Protein (Tus) Complexed With TerA DNA

Structural highlights

2i05 is a 3 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.6Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TUS_ECOLI Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2i05, resolution 2.60Å

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