1qjb: Difference between revisions

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-{{Seed}}
-[[Image:1qjb.png|left|200px]]
-<!--
+==14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 1)==
-The line below this paragraph, containing "STRUCTURE_1qjb", creates the "Structure Box" on the page.
+<StructureSection load='1qjb' size='340' side='right'caption='[[1qjb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1qjb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=14ps 14ps]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QJB FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
-{{STRUCTURE_1qjb|  PDB=1qjb  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qjb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjb OCA], [https://pdbe.org/1qjb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qjb RCSB], [https://www.ebi.ac.uk/pdbsum/1qjb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qjb ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/1433Z_HUMAN 1433Z_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.<ref>PMID:9360956</ref> <ref>PMID:14578935</ref> <ref>PMID:15071501</ref> <ref>PMID:15644438</ref> <ref>PMID:16376338</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qj/1qjb_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qjb ConSurf].
+<div style="clear:both"></div>
-===14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 1)===
+==See Also==
+*[[14-3-3 protein 3D structures|14-3-3 protein 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_10488331}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 10488331 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_10488331}}
-==About this Structure==
-QJB is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=14ps 14ps]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJB OCA].
-==Reference==
-<ref group="xtra">PMID:10488331</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Budman, J.]]
+[[Category: Large Structures]]
-[[Category: Cantley, L C.]]
+[[Category: Budman J]]
-[[Category: Gamblin, S J.]]
+[[Category: Cantley LC]]
-[[Category: Rittinger, K.]]
+[[Category: Gamblin SJ]]
-[[Category: Smerdon, S J.]]
+[[Category: Rittinger K]]
-[[Category: Volinia, S.]]
+[[Category: Smerdon SJ]]
-[[Category: Xu, J.]]
+[[Category: Volinia S]]
-[[Category: Yaffe, M B.]]
+[[Category: Xu J]]
-[[Category: 14-3-3]]
+[[Category: Yaffe MB]]
-[[Category: Phosphopeptide]]
-[[Category: Signal transducti]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:19:34 2009''