2hs8: Difference between revisions

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[[Image:2hs8.png|left|200px]]


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==Crystal structure of the Y364F mutant of 12-oxophytodienoate reductase 3 from tomato==
The line below this paragraph, containing "STRUCTURE_2hs8", creates the "Structure Box" on the page.
<StructureSection load='2hs8' size='340' side='right'caption='[[2hs8]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2hs8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HS8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HS8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
{{STRUCTURE_2hs8| PDB=2hs8 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hs8 OCA], [https://pdbe.org/2hs8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hs8 RCSB], [https://www.ebi.ac.uk/pdbsum/2hs8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hs8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OPR3_SOLLC OPR3_SOLLC] Specifically cleaves olefinic bonds in cyclic enones. Involved in the biosynthesis of jasmonic acid (JA) and perhaps in biosynthesis or metabolism of other oxylipin signaling moleclules. It is required for the spatial and temporal regulation of JA levels during dehiscence of anthers, promoting the stomium degeneration program (By similarity). In vitro, reduces 9S,13S-12-oxophytodienoic acid (9S,13S-OPDA) and 9R,13R-OPDA to 9S,13S-OPC-8:0 and 9R,13R-OPC-8:0, respectively.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hs/2hs8_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hs8 ConSurf].
<div style="clear:both"></div>


===Crystal structure of the Y364F mutant of 12-oxophytodienoate reductase 3 from tomato===
==See Also==
 
*[[12-oxophytodienoate reductase 3D structures|12-oxophytodienoate reductase 3D structures]]
 
__TOC__
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_16983071}}
 
==About this Structure==
2HS8 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HS8 OCA].
 
==Reference==
<ref group="xtra">PMID:16983071</ref><references group="xtra"/>
[[Category: 12-oxophytodienoate reductase]]
[[Category: Solanum lycopersicum]]
[[Category: Solanum lycopersicum]]
[[Category: Breithaupt, C.]]
[[Category: Breithaupt C]]
[[Category: Clausen, T.]]
[[Category: Clausen T]]
[[Category: Huber, R.]]
[[Category: Huber R]]
[[Category: Alpha beta 8 barrel]]
[[Category: Flavoprotein]]
[[Category: Jasmonate biosynthesis]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:43:33 2009''

Latest revision as of 12:34, 14 February 2024

Crystal structure of the Y364F mutant of 12-oxophytodienoate reductase 3 from tomatoCrystal structure of the Y364F mutant of 12-oxophytodienoate reductase 3 from tomato

Structural highlights

2hs8 is a 2 chain structure with sequence from Solanum lycopersicum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

OPR3_SOLLC Specifically cleaves olefinic bonds in cyclic enones. Involved in the biosynthesis of jasmonic acid (JA) and perhaps in biosynthesis or metabolism of other oxylipin signaling moleclules. It is required for the spatial and temporal regulation of JA levels during dehiscence of anthers, promoting the stomium degeneration program (By similarity). In vitro, reduces 9S,13S-12-oxophytodienoic acid (9S,13S-OPDA) and 9R,13R-OPDA to 9S,13S-OPC-8:0 and 9R,13R-OPC-8:0, respectively.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2hs8, resolution 1.90Å

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