1wv2: Difference between revisions
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New page: left|200px<br /><applet load="1wv2" size="450" color="white" frame="true" align="right" spinBox="true" caption="1wv2, resolution 2.9Å" /> '''Crystal structure of ... |
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== | ==Crystal structure of thiamine biosynthesis protein from Pseudomonas Aeruginosa== | ||
<StructureSection load='1wv2' size='340' side='right'caption='[[1wv2]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1wv2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WV2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WV2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wv2 OCA], [https://pdbe.org/1wv2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wv2 RCSB], [https://www.ebi.ac.uk/pdbsum/1wv2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wv2 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1wv2 TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/THIG_PSEAE THIG_PSEAE] Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wv/1wv2_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wv2 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pseudomonas aeruginosa]] | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Almo SC]] | |||
[[Category: Almo | [[Category: Burley SK]] | ||
[[Category: Burley | [[Category: Fedorov AA]] | ||
[[Category: Fedorov | [[Category: Fedorov EV]] | ||
[[Category: Fedorov | |||
Latest revision as of 16:34, 13 March 2024
Crystal structure of thiamine biosynthesis protein from Pseudomonas AeruginosaCrystal structure of thiamine biosynthesis protein from Pseudomonas Aeruginosa
Structural highlights
FunctionTHIG_PSEAE Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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