Hoelzer Sandbox: Difference between revisions
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='''<font color = 'black'> A Physical Model of the β2-Adrenergic Receptor</font>'''= | ='''<font color = 'black'> A Physical Model of the β2-Adrenergic Receptor</font>'''= | ||
=='''<font color = 'red'>A SMART Team Molecular Story</font><font color = 'black'> --- from the Madison West High School SMART Team</font>'''== | =='''<font color = 'red'>A SMART Team Molecular Story</font><font color = 'black'> --- from the Madison West High School 2008 SMART Team</font>'''== | ||
:Students -- Dianna Amasino, Axel Glaubitz, Susan Huang, Joy Li, Hsien-Yu Shih, Junyao Song, Esther Yoon, Xiao Zhu: | :Students -- Dianna Amasino, Axel Glaubitz, Susan Huang, Joy Li, Hsien-Yu Shih, Junyao Song, Esther Yoon, Xiao Zhu: | ||
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<applet load='2rh1.pdb' size='350' frame='true' align='left' scene=First_image/1'> | <applet load='2rh1.pdb' size='350' frame='true' align='left' scene='Hoelzer_Sandbox/First_image/1'/> | ||
<swf width="550" height="380">http://myweb.msoe.edu/~hoelzer/ | <swf width="550" height="380">http://myweb.msoe.edu/~hoelzer/Madison West 2007-2008.swf</swf> | ||
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==<font color = 'blue'>References</font>== | ==<font color = 'blue'>References</font>== | ||
1) Rasmussen, S.G.F., Choi, H.-J., Rosenbaum, D.M., Kobilka, T.S., Thian, F.S., Edwards, P.C., Burghammer, M., Ratnala, V.R.P., Sanishvili, R., Fischetti, R.F., Schertler, G.F.X., Weis, W.I. & Kobilka, B.K. (2007). “Crystal structure of the human [bgr]2 adrenergic G-protein-coupled receptor” Nature 450, 383-387. | |||
2) Cherezov, V., Rosenbaum, D.M., Hanson, M.A., Rasmussen, S.G.F., Thian, F.S., Kobilka, T.S., Choi, H.-J., Kuhn, P., Weis, W.I., Kobilka, B.K. & Stevens, R.C. (2007). “High-Resolution Crystal Structure of an Engineered Human 2-Adrenergic G Protein Coupled Receptor” Science 318, 1258-1265. | |||
3) Rosenbaum, D.M., Cherezov, V., Hanson, M.A., Rasmussen, S.G., Thian, F.S., Kobilka, T.S., Choi, H.J., Yao, X.J., Weis, W.I., Stevens, R.C. & Kobilka, B.K. (2007). “GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function” Science 318, 1266-1273. | |||
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We were able to present our project, poster, and our physical models at the 2008 ASBMB meeting in San Diego, CA. The poster was presented at the Medical College of Wisconsin and at the Scripps Research Institute. During our visit to Scripps, we met Art Olson and David Goodsell --- from the Molecular Graphics Laboratory at TSRI. | We were able to present our project, poster, and our physical models at the 2008 ASBMB meeting in San Diego, CA. The poster was presented at the Medical College of Wisconsin and at the Scripps Research Institute. During our visit to Scripps, we met Art Olson and David Goodsell --- from the Molecular Graphics Laboratory at TSRI. | ||
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==<font color = 'red'>MSOE Center for BioMolecular Modeling and SMART Teams</font>== | ==<font color = 'red'>MSOE Center for BioMolecular Modeling and SMART Teams</font>== | ||
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[[Image:Smart Teams photo 5.jpg|right|120px]] | [[Image:Smart Teams photo 5.jpg|right|120px]] | ||
<font color = 'red'>SMART Teams (S</font>tudents <font color = 'red'>M</font>odeling <font color = 'red'>A</font> <font color = 'red'>R</font>esearch <font color = 'red'>T</font>opic) is a science outreach program developed by the MSOE Center for BioMolecular Modeling. In this program, teams of high school students work with a local resarch lab to design and build a physical model of a protein that is being investigated by the lab. The goal of the SMART Team program is to introduce students to the real world of | <font color = 'red'>SMART Teams (S</font>tudents <font color = 'red'>M</font>odeling <font color = 'red'>A</font> <font color = 'red'>R</font>esearch <font color = 'red'>T</font>opic) is a science outreach program developed by the MSOE Center for BioMolecular Modeling. In this program, teams of high school students work with a local resarch lab to design and build a physical model of a protein that is being investigated by the lab. The goal of the SMART Team program is to introduce students to the real world of science --- as it exists in a local research lab. The development of this program was supported by grants from the NIH-NCRR SEPA program (Science Education Partnership Award) and an HHMI Precollege Science Education Award. For more information about this program, visit the CBM web site at [http://www.rpc.msoe.edu/cbm www.rpc.msoe.edu/cbm] . | ||