User:Wayne Decatur/SandboxIppo: Difference between revisions

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Homing Endonuclease
Homing Endonuclease


<table width='400' align='right' cellpadding='5'><tr><td rowspan='2'>&nbsp;</td><td bgcolor='#eeeeee'><applet load='1a73' size='390' frame='true' align='right' scene=' ' /></td></tr><tr><td bgcolor='#eeeeee'><center>'''I-Ppo''' (1a73), resolution 1.8&Aring; (<scene name='User:Wayne_Decatur/Plant_Viral_Protein_p19_Suppression_of_RNA_Silencing/View1/2'>initial scene</scene>).</center></td></tr></table>
<table width='400' align='right' cellpadding='4'><tr><td rowspan='2'>&nbsp;</td><td bgcolor='#eeeeee'><applet load='1a73' size='390' frame='true' align='right' scene=' ' /></td></tr><tr><td bgcolor='#eeeeee'><center>'''I-Ppo bound to DNA (cleaved product)''' (1a73), resolution 1.8&Aring; (<scene name='User:Wayne_Decatur/SandboxIppo/1a73alonefrommorph/2'>initial scene</scene>).</center></td></tr></table>
{{Structure
 
|PDB= 1a73 |SIZE=400|SCENE= |CAPTION= I-Ppo (1a73), resolution 1.8&Aring; (<scene name='User:Wayne_Decatur/Plant_Viral_Protein_p19_Suppression_of_RNA_Silencing/View1/2'>initial scene</scene>)
<ref>PMID:9665136</ref><ref>PMID: 10891275</ref>
|SITE=
 
|LIGAND=
<scene name='User:Wayne_Decatur/SandboxIppo/1evx21a73morph/5'>Morph of unbound DNA to bound, cleaved form.</scene><br> {{Button Toggle AnimationOnPause}}
|ACTIVITY=
 
|GENE=
I need to add back the Mg to the end of the morph and then remake these scene, or at least the User:Wayne_Decatur/SandboxIppo/1a73alonefrommorph/ view.
|DOMAIN=
 
|RELATEDENTRY=
{{Link Toggle FancyCartoonHighQualityView}}.
|RESOURCES=<span class='plainlinks'><!--[http://www-unix.oit.umass.edu/~wdecatur/p19tutorial/ Explorable Tour], Eric Martz felt no one would look here-->[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a73 OCA], [http://www.ebi.ac.uk/pdbsum/1a73 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1a73 RCSB]</span>
 
}}
{{reflist}}
 
==See also==
*[[User:Wayne Decatur/I-Ppo Morph Methods]]
*[[H-N-H motif]]

Latest revision as of 05:31, 27 January 2011

I-Ppo II-Ppo I

Homing Endonuclease

 

PDB ID 1a73

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I-Ppo bound to DNA (cleaved product) (1a73), resolution 1.8Å ().

[1][2]



I need to add back the Mg to the end of the morph and then remake these scene, or at least the User:Wayne_Decatur/SandboxIppo/1a73alonefrommorph/ view.

.

  1. Flick KE, Jurica MS, Monnat RJ Jr, Stoddard BL. DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI. Nature. 1998 Jul 2;394(6688):96-101. PMID:9665136 doi:10.1038/27952
  2. Galburt EA, Chadsey MS, Jurica MS, Chevalier BS, Erho D, Tang W, Monnat RJ Jr, Stoddard BL. Conformational changes and cleavage by the homing endonuclease I-PpoI: a critical role for a leucine residue in the active site. J Mol Biol. 2000 Jul 21;300(4):877-87. PMID:10891275 doi:10.1006/jmbi.2000.3874

See alsoSee also