User:Tom Gluick/glutamine synthetase/Assignment 3: Difference between revisions

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Tom Gluick (talk | contribs)
 
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==Assignment and Intent==
==Assignment and Intent==
<span style="color:red">'''Assignment 3:  IIB. Tertiary Structure:'''</span>  Map the two CATH domains in the GS; Include in your discussion what CATH database records<ref>Pearl, F., ''et.al.''The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis, Nucl. Acids Res. 2005 22: D247-D252</ref>; explain the significance of each domain.  In your discussion show the features of the CATH  architecture and topology that provides them with the designation.  As a hint you may want to use the Jena Library Jmol[http://www.imb-jena.de/IMAGE.html], which can be access through PDBsum[http://www.ebi.ac.uk/pdbsum/] to assist you in mapping the CATH domains. The RSCB site may not list the domains correctly.[http://www.rcsb.org/pdb/home/home.do] <ref name="review"/><br/>
<span style="color:red">Intent and Hope: </span>  I hoped the students would be able to illustrate the domains and structures of glutamine synthetase as defined by CATH website. I hoped the students would incorporate information found in the references into their presentation.


==Student Contribution==
==Student Contribution==
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===Student Contributions===
===Student Contributions===


Undergraduate student at UMBC, Group consisits of Sindhu Lakkur, Ejiofor Ezekwe and Steven Tuyishime- Dr. Thomas Gluick Biol 430
Sindhu Lakkur<br/> Ejiofor Ezekwe<br/> Steven Tuyishime
 
==Assessment==
 
The students completed the assignment successfully.  They showed the two domains in the context of the complex, showed each domain and its architecture using the SAT.  The visuals were designed very well. The assignment was relatively straightforward with most information easily accessible.