2f2e: Difference between revisions

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-{{Seed}}
-[[Image:2f2e.png|left|200px]]
-<!--
+==Crystal Structure of PA1607, a Putative Transcription Factor==
-The line below this paragraph, containing "STRUCTURE_2f2e", creates the "Structure Box" on the page.
+<StructureSection load='2f2e' size='340' side='right'caption='[[2f2e]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2f2e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F2E FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-{{STRUCTURE_2f2e|  PDB=2f2e  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2e OCA], [https://pdbe.org/2f2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f2e RCSB], [https://www.ebi.ac.uk/pdbsum/2f2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f2e ProSAT], [https://www.topsan.org/Proteins/MCSG/2f2e TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q9I3B4_PSEAE Q9I3B4_PSEAE]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/2f2e_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f2e ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The structure of the PA1607 protein from Pseudomonas aureginosa was determined at 1.85 A resolution using the Se-Met multiwavelength anomalous diffraction (MAD) technique. PA1607 forms a dimer and adopts a winged-helix motif similar to the MarR family of transcription regulators, though it has an unusual dimerization profile. The DNA-binding regions and a putative metal-binding site are not conserved in PA1607.
-===Crystal Structure of PA1607, a Putative Transcription Factor===
+The X-ray crystal structure of PA1607 from Pseudomonas aureginosa at 1.9 A resolution--a putative transcription factor.,Sieminska EA, Xu X, Savchenko A, Sanders DA Protein Sci. 2007 Mar;16(3):543-9. PMID:17322537<ref>PMID:17322537</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<!--
+</div>
-The line below this paragraph, {{ABSTRACT_PUBMED_17322537}}, adds the Publication Abstract to the page
+<div class="pdbe-citations 2f2e" style="background-color:#fffaf0;"></div>
-(as it appears on PubMed at http://www.pubmed.gov), where 17322537 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_17322537}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Large Structures]]
-F2E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2E OCA].
-==Reference==
-The X-ray crystal structure of PA1607 from Pseudomonas aureginosa at 1.9 A resolution--a putative transcription factor., Sieminska EA, Xu X, Savchenko A, Sanders DA, Protein Sci. 2007 Mar;16(3):543-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17322537 17322537]
 [[Category: Pseudomonas aeruginosa]]
-[[Category: Single protein]]
+[[Category: Cuff M]]
-[[Category: Cuff, M.]]
+[[Category: Edwards A]]
-[[Category: Edwards, A.]]
+[[Category: Joachimiak A]]
-[[Category: Joachimiak, A.]]
+[[Category: Lunin V]]
-[[Category: Lunin, V.]]
+[[Category: Sanders DA]]
-[[Category: MCSG, Midwest Center for Structural Genomics.]]
+[[Category: Savchenko A]]
-[[Category: Sanders, D A.]]
+[[Category: Sieminska EA]]
-[[Category: Savchenko, A.]]
+[[Category: Xu X]]
-[[Category: Sieminska, E A.]]
+[[Category: Zheng H]]
-[[Category: Xu, X.]]
-[[Category: Zheng, H.]]
-[[Category: Apc5613]]
-[[Category: Dna binding protein/structural genomics complex]]
-[[Category: Helix-trun-helix]]
-[[Category: Mcsg]]
-[[Category: Midwest center for structural genomic]]
-[[Category: Protein structure initiative]]
-[[Category: Psi]]
-[[Category: Structural genomic]]
-[[Category: Transcription factor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 19 20:10:50 2008''