1u1s: Difference between revisions

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-{{Seed}}
-[[Image:1u1s.png|left|200px]]
-<!--
+==Hfq protein from Pseudomonas aeruginosa. Low-salt crystals==
-The line below this paragraph, containing "STRUCTURE_1u1s", creates the "Structure Box" on the page.
+<StructureSection load='1u1s' size='340' side='right'caption='[[1u1s]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1u1s]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U1S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U1S FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u1s OCA], [https://pdbe.org/1u1s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u1s RCSB], [https://www.ebi.ac.uk/pdbsum/1u1s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u1s ProSAT], [https://www.topsan.org/Proteins/RSGI/1u1s TOPSAN]</span></td></tr>
-{{STRUCTURE_1u1s|  PDB=1u1s  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HFQ_PSEAE HFQ_PSEAE] RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u1/1u1s_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u1s ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The structure of the Hfq protein from Pseudomonas aeruginosa was determined using two different ionic conditions. In both cases the molecules formed identical hexameric rings, but some variations in the crystal packing were revealed. Hfq belongs to the family of Sm/LSm proteins, the members of which can form hexameric as well as heptameric rings. Comparative analysis of known structures of this protein family shows that the fragment of the Sm-fold responsible for oligomerization is strongly structurally conserved. In the heptameric ring, three conserved hydrogen bonds between beta-strands of adjacent molecules hold together the monomers, whereas in the hexameric rings of Hfq an additional conserved inaccessible hydrogen bond between neighbouring monomers is observed.
-===Hfq protein from Pseudomonas aeruginosa. Low-salt crystals===
+Structure of Pseudomonas aeruginosa Hfq protein.,Nikulin A, Stolboushkina E, Perederina A, Vassilieva I, Blaesi U, Moll I, Kachalova G, Yokoyama S, Vassylyev D, Garber M, Nikonov S Acta Crystallogr D Biol Crystallogr. 2005 Feb;61(Pt 2):141-6. Epub 2005, Jan 19. PMID:15681864<ref>PMID:15681864</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 1u1s" style="background-color:#fffaf0;"></div>
-<!--
+==See Also==
-The line below this paragraph, {{ABSTRACT_PUBMED_15681864}}, adds the Publication Abstract to the page
+*[[Protein Hfq|Protein Hfq]]
-(as it appears on PubMed at http://www.pubmed.gov), where 15681864 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_15681864}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Large Structures]]
-U1S is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U1S OCA].
-==Reference==
-Structure of Pseudomonas aeruginosa Hfq protein., Nikulin A, Stolboushkina E, Perederina A, Vassilieva I, Blaesi U, Moll I, Kachalova G, Yokoyama S, Vassylyev D, Garber M, Nikonov S, Acta Crystallogr D Biol Crystallogr. 2005 Feb;61(Pt 2):141-6. Epub 2005, Jan 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15681864 15681864]
 [[Category: Pseudomonas aeruginosa]]
-[[Category: Blaesi, U.]]
+[[Category: Blaesi U]]
-[[Category: Garber, M.]]
+[[Category: Garber M]]
-[[Category: Kachalova, G.]]
+[[Category: Kachalova G]]
-[[Category: Moll, I.]]
+[[Category: Moll I]]
-[[Category: Nikonov, S V.]]
+[[Category: Nikonov SV]]
-[[Category: Nikulin, A D.]]
+[[Category: Nikulin AD]]
-[[Category: Perederina, I.]]
+[[Category: Perederina I]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Stolboushkina EA]]
-[[Category: Stolboushkina, E A.]]
+[[Category: Vassilieva IM]]
-[[Category: Vassilieva, I M.]]
+[[Category: Vassylyev D]]
-[[Category: Vassylyev, D.]]
+[[Category: Yokoyama S]]
-[[Category: Yokoyama, S.]]
-[[Category: Hf1]]
-[[Category: Hfq]]
-[[Category: Riken structural genomics/proteomics initiative]]
-[[Category: Rsgi]]
-[[Category: Sm-like bacterial protein]]
-[[Category: Structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 15:54:43 2008''