2dwc: Difference between revisions

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-{{Seed}}
-[[Image:2dwc.png|left|200px]]
-<!--
+==Crystal structure of Probable phosphoribosylglycinamide formyl transferase from Pyrococcus horikoshii OT3 complexed with ADP==
-The line below this paragraph, containing "STRUCTURE_2dwc", creates the "Structure Box" on the page.
+<StructureSection load='2dwc' size='340' side='right'caption='[[2dwc]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2dwc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DWC FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-{{STRUCTURE_2dwc|  PDB=2dwc  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dwc OCA], [https://pdbe.org/2dwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dwc RCSB], [https://www.ebi.ac.uk/pdbsum/2dwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dwc ProSAT], [https://www.topsan.org/Proteins/RSGI/2dwc TOPSAN]</span></td></tr>
+</table>
-===Crystal structure of Probable phosphoribosylglycinamide formyl transferase from Pyrococcus horikoshii OT3 complexed with ADP===
+== Function ==
+[https://www.uniprot.org/uniprot/PURT_PYRHO PURT_PYRHO] Catalyzes two reactions: the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR; the second, a side reaction, is the production of acetyl phosphate and ADP from acetate and ATP.[HAMAP-Rule:MF_01643]
+== Evolutionary Conservation ==
-==About this Structure==
+[[Image:Consurf_key_small.gif|200px|right]]
-DWC is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DWC OCA].
+Check<jmol>
-[[Category: Pyrococcus horikoshii]]
+  <jmolCheckbox>
-[[Category: Arai, R.]]
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dw/2dwc_consurf.spt"</scriptWhenChecked>
-[[Category: Kamo-Uchikubo, T.]]
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+    <text>to colour the structure by Evolutionary Conservation</text>
-[[Category: Shirouzu, M.]]
+  </jmolCheckbox>
-[[Category: Yokoyama, S.]]
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dwc ConSurf].
-[[Category: Yoshikawa, S.]]
+<div style="clear:both"></div>
-[[Category: National project on protein structural and functional analyse]]
+__TOC__
-[[Category: Nppsfa]]
+</StructureSection>
-[[Category: Phosphoribosylglycinamide formyltransferase]]
+[[Category: Large Structures]]
-[[Category: Purine ribonucleotide biosynthesis]]
+[[Category: Pyrococcus horikoshii OT3]]
-[[Category: Purt]]
+[[Category: Arai R]]
-[[Category: Riken structural genomics/proteomics initiative]]
+[[Category: Kamo-Uchikubo T]]
-[[Category: Rsgi]]
+[[Category: Shirouzu M]]
-[[Category: Structural genomic]]
+[[Category: Yokoyama S]]
+[[Category: Yoshikawa S]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 15:32:42 2008''