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==Crystal Structure of Protein of Unknown Function PA94 from Pseudomonas aeruginosa, Putative Regulator== | |||
<StructureSection load='1tu1' size='340' side='right'caption='[[1tu1]], [[Resolution|resolution]] 1.95Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1tu1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TU1 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tu1 OCA], [https://pdbe.org/1tu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tu1 RCSB], [https://www.ebi.ac.uk/pdbsum/1tu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tu1 ProSAT], [https://www.topsan.org/Proteins/MCSG/1tu1 TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/EAGT6_PSEAE EAGT6_PSEAE] Plays an essential role in toxin Tse6 delivery to target cells and specifically in the loading of Tse6 onto VgrG1a.<ref>PMID:30177742</ref> | |||
== Evolutionary Conservation == | |||
== | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
[[ | <jmolCheckbox> | ||
[[ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tu/1tu1_consurf.spt"</scriptWhenChecked> | ||
[[ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
[[ | <text>to colour the structure by Evolutionary Conservation</text> | ||
[ | </jmolCheckbox> | ||
[[ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tu1 ConSurf]. | ||
[ | <div style="clear:both"></div> | ||
[ | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Pseudomonas aeruginosa PAO1]] | ||
[[Category: | [[Category: Cymborowski M]] | ||
[[Category: | [[Category: Edwards A]] | ||
[[Category: | [[Category: Evdokimova E]] | ||
[[Category: Joachimiak A]] | |||
[[Category: Minor W]] | |||
[[Category: Osipiuk J]] | |||
[[Category: Savchenko A]] |
Latest revision as of 11:42, 14 February 2024
Crystal Structure of Protein of Unknown Function PA94 from Pseudomonas aeruginosa, Putative RegulatorCrystal Structure of Protein of Unknown Function PA94 from Pseudomonas aeruginosa, Putative Regulator
Structural highlights
FunctionEAGT6_PSEAE Plays an essential role in toxin Tse6 delivery to target cells and specifically in the loading of Tse6 onto VgrG1a.[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. References
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