2yz8: Difference between revisions

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-{{Seed}}
-[[Image:2yz8.png|left|200px]]
-<!--
+==Crystal structure of the 32th Ig-like domain of human obscurin (KIAA1556)==
-The line below this paragraph, containing "STRUCTURE_2yz8", creates the "Structure Box" on the page.
+<StructureSection load='2yz8' size='340' side='right'caption='[[2yz8]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2yz8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YZ8 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-{{STRUCTURE_2yz8|  PDB=2yz8  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yz8 OCA], [https://pdbe.org/2yz8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yz8 RCSB], [https://www.ebi.ac.uk/pdbsum/2yz8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yz8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2yz8 TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/OBSCN_HUMAN OBSCN_HUMAN] Involved in myofibrillogenesis. Seems to be involved in assembly of myosin into sarcomeric A bands in striated muscle. Isoform 3 together with ANK1 isoform Mu17/Ank1.5 may provide a molecular link between the sarcoplasmic reticulum and myofibrils.<ref>PMID:11448995</ref> <ref>PMID:16205939</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yz/2yz8_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yz8 ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of the 32th Ig-like domain of human obscurin (KIAA1556)===
+==See Also==
+*[[Obscurin|Obscurin]]
+== References ==
-==About this Structure==
+<references/>
-YZ8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZ8 OCA].
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Chen, L.]]
+[[Category: Large Structures]]
-[[Category: Chrzas, J.]]
+[[Category: Chen L]]
-[[Category: Fu, Z Q.]]
+[[Category: Chrzas J]]
-[[Category: Kishishita, S.]]
+[[Category: Fu ZQ]]
-[[Category: Nishino, A.]]
+[[Category: Kishishita S]]
-[[Category: Ohsawa, N.]]
+[[Category: Nishino A]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Ohsawa N]]
-[[Category: Saijo, S.]]
+[[Category: Saijo S]]
-[[Category: Shirouzu, M.]]
+[[Category: Shirouzu M]]
-[[Category: Wang, B C.]]
+[[Category: Wang BC]]
-[[Category: Yokoyama, S.]]
+[[Category: Yokoyama S]]
-[[Category: Ig fold]]
+[[Category: Z-disk]]
-[[Category: Kiaa1556]]
-[[Category: National project on protein structural and functional analyse]]
-[[Category: Nppsfa]]
-[[Category: Obsucurin]]
-[[Category: Riken structural genomics/proteomics initiative]]
-[[Category: Rsgi]]
-[[Category: Structural genomic]]
-[[Category: Structural protein]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 13:29:49 2008''