2q7z: Difference between revisions

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[[Image:2q7z.png|left|200px]]


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==Solution Structure of the 30 SCR domains of human Complement Receptor 1==
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<StructureSection load='2q7z' size='340' side='right'caption='[[2q7z]]' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2q7z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q7Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q7Z FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray solution scattering</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q7z OCA], [https://pdbe.org/2q7z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q7z RCSB], [https://www.ebi.ac.uk/pdbsum/2q7z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q7z ProSAT]</span></td></tr>
{{STRUCTURE_2q7z|  PDB=2q7z  |  SCENE=  }}
</table>
 
== Function ==
===Solution Structure of the 30 SCR domains of human Complement Receptor 1===
[https://www.uniprot.org/uniprot/CR1_HUMAN CR1_HUMAN] Mediates cellular binding of particles and immune complexes that have activated complement.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2q7z ConSurf].
2Q7Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q7Z OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
The partly folded back solution structure arrangement of the 30 SCR domains in human complement receptor type 1 (CR1) permits access to its C3b and C4b ligands., Furtado PB, Huang CY, Ihyembe D, Hammond RA, Marsh HC, Perkins SJ, J Mol Biol. 2008 Jan 4;375(1):102-18. Epub 2007 Oct 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18028942 18028942]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Furtado, P B.]]
[[Category: Furtado PB]]
[[Category: Hammond, R A.]]
[[Category: Hammond RA]]
[[Category: Huang, C Y.]]
[[Category: Huang CY]]
[[Category: Ihyembe, D.]]
[[Category: Ihyembe D]]
[[Category: Marsh, H C.]]
[[Category: Marsh HC]]
[[Category: Perkins, S J.]]
[[Category: Perkins SJ]]
[[Category: Blood group antigen]]
[[Category: Complement]]
[[Category: Complement pathway]]
[[Category: Glycoprotein]]
[[Category: Immune response]]
[[Category: Immune system]]
[[Category: Innate immunity]]
[[Category: Membrane]]
[[Category: Polymorphism]]
[[Category: Pyrrolidone carboxylic acid]]
[[Category: Receptor]]
[[Category: Scr domain]]
[[Category: Sushi]]
[[Category: Transmembrane]]
 
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