2orv: Difference between revisions

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OCA

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-{{Seed}}
-[[Image:2orv.png|left|200px]]
-<!--
+==human Thymidine Kinase 1 in complex with TP4A==
-The line below this paragraph, containing "STRUCTURE_2orv", creates the "Structure Box" on the page.
+<StructureSection load='2orv' size='340' side='right'caption='[[2orv]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2orv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ORV FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4TA:P1-(5-ADENOSYL)P4-(5-(2-DEOXY-THYMIDYL))TETRAPHOSPHATE'>4TA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_2orv|  PDB=2orv  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2orv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orv OCA], [https://pdbe.org/2orv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2orv RCSB], [https://www.ebi.ac.uk/pdbsum/2orv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2orv ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/KITH_HUMAN KITH_HUMAN]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/or/2orv_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2orv ConSurf].
+<div style="clear:both"></div>
-===human Thymidine Kinase 1 in complex with TP4A===
+==See Also==
+*[[Thymidine kinase 3D structures|Thymidine kinase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_17407781}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 17407781 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_17407781}}
-==About this Structure==
-ORV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORV OCA].
-==Reference==
-Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure., Segura-Pena D, Lutz S, Monnerjahn C, Konrad M, Lavie A, J Mol Biol. 2007 May 25;369(1):129-41. Epub 2007 Mar 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17407781 17407781]
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Thymidine kinase]]
+[[Category: Konrad M]]
-[[Category: Konrad, M.]]
+[[Category: Lavie A]]
-[[Category: Lavie, A.]]
+[[Category: Lutz S]]
-[[Category: Lutz, S.]]
+[[Category: Monnerjahn C]]
-[[Category: Monnerjahn, C.]]
+[[Category: Segura-Pena D]]
-[[Category: Segura-Pena, D.]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:20:15 2008''