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==NMR SOLUTION STRUCTURE OF HUMAN NEUROPEPTIDE Y== | |||
<StructureSection load='1ron' size='340' side='right'caption='[[1ron]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1ron]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The May 2012 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Leptin'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2012_5 10.2210/rcsb_pdb/mom_2012_5]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RON FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ron FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ron OCA], [https://pdbe.org/1ron PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ron RCSB], [https://www.ebi.ac.uk/pdbsum/1ron PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ron ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NPY_HUMAN NPY_HUMAN] NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | |||
== Evolutionary Conservation == | |||
< | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ro/1ron_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
== | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ron ConSurf]. | |||
<div style="clear:both"></div> | |||
== | __TOC__ | ||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Leptin]] | ||
[[Category: | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: | [[Category: Howlett GJ]] | ||
[[Category: | [[Category: Karagianis G]] | ||
[[Category: | [[Category: Monks SA]] | ||
[[Category: | [[Category: Norton RS]] | ||
Latest revision as of 11:25, 1 May 2024
NMR SOLUTION STRUCTURE OF HUMAN NEUROPEPTIDE YNMR SOLUTION STRUCTURE OF HUMAN NEUROPEPTIDE Y
Structural highlights
FunctionNPY_HUMAN NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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