1nyh: Difference between revisions

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[[Image:1nyh.png|left|200px]]


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==Crystal Structure of the Coiled-coil Dimerization Motif of Sir4==
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<StructureSection load='1nyh' size='340' side='right'caption='[[1nyh]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1nyh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NYH FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nyh OCA], [https://pdbe.org/1nyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nyh RCSB], [https://www.ebi.ac.uk/pdbsum/1nyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nyh ProSAT]</span></td></tr>
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</table>
 
== Function ==
===Crystal Structure of the Coiled-coil Dimerization Motif of Sir4===
[https://www.uniprot.org/uniprot/SIR4_YEAST SIR4_YEAST] The proteins SIR1 through SIR4 are required for transcriptional repression of the silent mating type loci, HML and HMR. The proteins SIR2 through SIR4 repress mulitple loci by modulating chromatin structure. Involves the compaction of chromatin fiber into a more condensed form.<ref>PMID:18039933</ref>
 
== References ==
 
<references/>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_12791253}}
 
==About this Structure==
1NYH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NYH OCA].  
 
==Reference==
Structure of the coiled-coil dimerization motif of Sir4 and its interaction with Sir3., Chang JF, Hall BE, Tanny JC, Moazed D, Filman D, Ellenberger T, Structure. 2003 Jun;11(6):637-49. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12791253 12791253]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Chang JF]]
[[Category: Chang, J F.]]
[[Category: Ellenberger T]]
[[Category: Ellenberger, T.]]
[[Category: Filman D]]
[[Category: Filman, D.]]
[[Category: Hall BE]]
[[Category: Hall, B E.]]
[[Category: Moazed D]]
[[Category: Moazed, D.]]
[[Category: Tanny JC]]
[[Category: Tanny, J C.]]
[[Category: Coiled-coil]]
[[Category: Repressor]]
[[Category: Transcription regulation]]
 
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