1f0l: Difference between revisions

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OCA

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-[[Image:1f0l.gif|left|200px]]<br />
-<applet load="1f0l" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="1f0l, resolution 1.55&Aring;" />
-'''1.55 ANGSTROM CRYSTAL STRUCTURE OF WILD TYPE DIPHTHERIA TOXIN'''<br />
-==About this Structure==
+==1.55 ANGSTROM CRYSTAL STRUCTURE OF WILD TYPE DIPHTHERIA TOXIN==
-F0L is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]] with CL and APU as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1F0L OCA]].
+<StructureSection load='1f0l' size='340' side='right'caption='[[1f0l]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1f0l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F0L FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APU:ADENYLYL-3-5-PHOSPHO-URIDINE-3-MONOPHOSPHATE'>APU</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f0l OCA], [https://pdbe.org/1f0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f0l RCSB], [https://www.ebi.ac.uk/pdbsum/1f0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f0l ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DTX_CORBE DTX_CORBE] Diphtheria toxin, produced by a phage infecting Corynebacterium diphtheriae, is a proenzyme that, after activation, catalyzes the covalent attachment of the ADP ribose moiety of NAD to eukaryotic elongation factor 2 (eEF-2). Fragment A is the catalytic portion responsible for enzymatic ADP-ribosylation of elongation factor 2, while fragment B is responsible for binding of toxin to cell receptors and entry of fragment A.<ref>PMID:18276581</ref> <ref>PMID:19793133</ref>
+==See Also==
+*[[Diphtheria toxin|Diphtheria toxin]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Corynebacterium diphtheriae]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Eisenberg, D.]]
+[[Category: Eisenberg D]]
-[[Category: Steere, B.]]
+[[Category: Steere B]]
-[[Category: APU]]
-[[Category: CL]]
-[[Category: adp-ribosylation]]
-[[Category: bacterial toxin]]
-[[Category: transmembrane]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 20:37:11 2007''