2pxr: Difference between revisions

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[[Image:2pxr.png|left|200px]]


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==Crystal Structure of HIV-1 CA146 in the Presence of CAP-1==
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<StructureSection load='2pxr' size='340' side='right'caption='[[2pxr]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2pxr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PXR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PXR FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_2pxr|  PDB=2pxr  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pxr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pxr OCA], [https://pdbe.org/2pxr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pxr RCSB], [https://www.ebi.ac.uk/pdbsum/2pxr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pxr ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of HIV-1 CA146 in the Presence of CAP-1===
== Function ==
 
[https://www.uniprot.org/uniprot/Q79791_9HIV1 Q79791_9HIV1] Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity).[SAAS:SAAS000071_004_008806]  Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity).[SAAS:SAAS000071_004_011858]
 
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{{ABSTRACT_PUBMED_17826792}}
 
==About this Structure==
2PXR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PXR OCA].  
 
==Reference==
Structure of the antiviral assembly inhibitor CAP-1 complex with the HIV-1 CA protein., Kelly BN, Kyere S, Kinde I, Tang C, Howard BR, Robinson H, Sundquist WI, Summers MF, Hill CP, J Mol Biol. 2007 Oct 19;373(2):355-66. Epub 2007 Aug 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17826792 17826792]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Kelly, B N.]]
[[Category: Kelly BN]]
[[Category: Anti-viral]]
[[Category: Hiv-1]]
[[Category: Small molecule inhibition]]
[[Category: Viral capsid]]
[[Category: Viral protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 18:53:27 2008''

Latest revision as of 12:12, 21 February 2024

Crystal Structure of HIV-1 CA146 in the Presence of CAP-1Crystal Structure of HIV-1 CA146 in the Presence of CAP-1

Structural highlights

2pxr is a 1 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.5Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q79791_9HIV1 Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity).[SAAS:SAAS000071_004_008806] Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity).[SAAS:SAAS000071_004_011858]

2pxr, resolution 1.50Å

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OCA
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