1nhg: Difference between revisions

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-{{Seed}}
-[[Image:1nhg.png|left|200px]]
-<!--
+==CRYSTAL STRUCTURE ANALYSIS OF PLASMODIUM FALCIPARUM ENOYL-ACYL-CARRIER-PROTEIN REDUCTASE WITH TRICLOSAN==
-The line below this paragraph, containing "STRUCTURE_1nhg", creates the "Structure Box" on the page.
+<StructureSection load='1nhg' size='340' side='right'caption='[[1nhg]], [[Resolution|resolution]] 2.43&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1nhg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NHG FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.43&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCL:TRICLOSAN'>TCL</scene></td></tr>
-{{STRUCTURE_1nhg|  PDB=1nhg  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nhg OCA], [https://pdbe.org/1nhg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nhg RCSB], [https://www.ebi.ac.uk/pdbsum/1nhg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nhg ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q9BH77_PLAFA Q9BH77_PLAFA]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nh/1nhg_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nhg ConSurf].
+<div style="clear:both"></div>
-===CRYSTAL STRUCTURE ANALYSIS OF PLASMODIUM FALCIPARUM ENOYL-ACYL-CARRIER-PROTEIN REDUCTASE WITH TRICLOSAN===
+==See Also==
+*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_11792710}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 11792710 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_11792710}}
-==About this Structure==
-NHG is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NHG OCA].
-==Reference==
-Structural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductase., Perozzo R, Kuo M, Sidhu AS, Valiyaveettil JT, Bittman R, Jacobs WR Jr, Fidock DA, Sacchettini JC, J Biol Chem. 2002 Apr 12;277(15):13106-14. Epub 2002 Jan 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11792710 11792710]
 [[Category: Plasmodium falciparum]]
-[[Category: Protein complex]]
+[[Category: Bittman R]]
-[[Category: Bittman, R.]]
+[[Category: Fidock DA]]
-[[Category: Fidock, D A.]]
+[[Category: Jacobs Jr WR]]
-[[Category: Jr., W R.Jacobs.]]
+[[Category: Kuo M]]
-[[Category: Kuo, M.]]
+[[Category: Perozzo R]]
-[[Category: Perozzo, R.]]
+[[Category: Sacchettini JC]]
-[[Category: Sacchettini, J C.]]
+[[Category: Sidhu AS]]
-[[Category: Sidhu, A S.]]
+[[Category: Valiyaveettil JT]]
-[[Category: Valiyaveettil, J T.]]
-[[Category: Nadh]]
-[[Category: Rossmann fold]]
-[[Category: Short chain dehydrogenase reductase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 14:58:59 2008''