1oyr: Difference between revisions

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[[Image:1oyr.png|left|200px]]


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==Crystal structure of the phosphorolytic exoribonuclease RNase PH from Bacillus subtilis==
The line below this paragraph, containing "STRUCTURE_1oyr", creates the "Structure Box" on the page.
<StructureSection load='1oyr' size='340' side='right'caption='[[1oyr]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1oyr]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OYR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OYR FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1oyr| PDB=1oyr |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oyr OCA], [https://pdbe.org/1oyr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oyr RCSB], [https://www.ebi.ac.uk/pdbsum/1oyr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oyr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RNPH_BACSU RNPH_BACSU] Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates. Plays a role in the secondary pathway of 23S rRNA 3' end maturation.<ref>PMID:19880604</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oy/1oyr_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oyr ConSurf].
<div style="clear:both"></div>


===Crystal structure of the phosphorolytic exoribonuclease RNase PH from Bacillus subtilis===
==See Also==
 
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
== References ==
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{{ABSTRACT_PUBMED_14767080}}
 
==About this Structure==
1OYR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OYR OCA].
 
==Reference==
Crystal structure of the phosphorolytic exoribonuclease RNase PH from Bacillus subtilis and implications for its quaternary structure and tRNA binding., Harlow LS, Kadziola A, Jensen KF, Larsen S, Protein Sci. 2004 Mar;13(3):668-77. Epub 2004 Feb 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14767080 14767080]
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: TRNA nucleotidyltransferase]]
[[Category: Harlow LS]]
[[Category: Harlow, L S.]]
[[Category: Jensen KF]]
[[Category: Jensen, K F.]]
[[Category: Kadziola A]]
[[Category: Kadziola, A.]]
[[Category: Larsen S]]
[[Category: Larsen, S.]]
[[Category: Transferase]]
[[Category: Trna processing]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:48:53 2008''

Latest revision as of 11:04, 14 February 2024

Crystal structure of the phosphorolytic exoribonuclease RNase PH from Bacillus subtilisCrystal structure of the phosphorolytic exoribonuclease RNase PH from Bacillus subtilis

Structural highlights

1oyr is a 6 chain structure with sequence from Bacillus subtilis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.1Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RNPH_BACSU Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates. Plays a role in the secondary pathway of 23S rRNA 3' end maturation.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Redko Y, Condon C. Maturation of 23S rRNA in Bacillus subtilis in the absence of Mini-III. J Bacteriol. 2010 Jan;192(1):356-9. doi: 10.1128/JB.01096-09. Epub . PMID:19880604 doi:http://dx.doi.org/10.1128/JB.01096-09

1oyr, resolution 3.10Å

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