1wu9: Difference between revisions

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-{{Seed}}
-[[Image:1wu9.png|left|200px]]
-<!--
+==Crystal structure of the C-terminal domain of the end-binding protein 1 (EB1)==
-The line below this paragraph, containing "STRUCTURE_1wu9", creates the "Structure Box" on the page.
+<StructureSection load='1wu9' size='340' side='right'caption='[[1wu9]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1wu9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WU9 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.54&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wu9 OCA], [https://pdbe.org/1wu9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wu9 RCSB], [https://www.ebi.ac.uk/pdbsum/1wu9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wu9 ProSAT]</span></td></tr>
-{{STRUCTURE_1wu9|  PDB=1wu9  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/MARE1_HUMAN MARE1_HUMAN] Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.<ref>PMID:12388762</ref> <ref>PMID:21646404</ref> <ref>PMID:16109370</ref> <ref>PMID:19632184</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/1wu9_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wu9 ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of the C-terminal domain of the end-binding protein 1 (EB1)===
+==See Also==
+*[[End-binding protein|End-binding protein]]
+*[[Microtubule-associated protein 3D structures|Microtubule-associated protein 3D structures]]
-<!--
+== References ==
-The line below this paragraph, {{ABSTRACT_PUBMED_15616574}}, adds the Publication Abstract to the page
+<references/>
-(as it appears on PubMed at http://www.pubmed.gov), where 15616574 is the PubMed ID number.
+__TOC__
--->
+</StructureSection>
-{{ABSTRACT_PUBMED_15616574}}
-==About this Structure==
-WU9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WU9 OCA].
-==Reference==
-Structural insights into the EB1-APC interaction., Honnappa S, John CM, Kostrewa D, Winkler FK, Steinmetz MO, EMBO J. 2005 Jan 26;24(2):261-9. Epub 2004 Dec 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15616574 15616574]
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Honnappa, S.]]
+[[Category: Honnappa S]]
-[[Category: John, C M.]]
+[[Category: John CM]]
-[[Category: Kostrewa, D.]]
+[[Category: Kostrewa D]]
-[[Category: Steinmetz, M O.]]
+[[Category: Steinmetz MO]]
-[[Category: Winkler, F K.]]
+[[Category: Winkler FK]]
-[[Category: Apc/dynactin binding domain]]
-[[Category: Coiled coil]]
-[[Category: Eb1-like structural motif]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 08:43:44 2008''