1msc: Difference between revisions

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-{{Seed}}
-[[Image:1msc.png|left|200px]]
-<!--
+==CRYSTAL STRUCTURE OF MS2 COAT PROTEIN DIMER==
-The line below this paragraph, containing "STRUCTURE_1msc", creates the "Structure Box" on the page.
+<StructureSection load='1msc' size='340' side='right'caption='[[1msc]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1msc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MSC FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1msc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msc OCA], [https://pdbe.org/1msc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1msc RCSB], [https://www.ebi.ac.uk/pdbsum/1msc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1msc ProSAT]</span></td></tr>
-{{STRUCTURE_1msc|  PDB=1msc  |  SCENE=  }}
+</table>
+== Function ==
-===CRYSTAL STRUCTURE OF MS2 COAT PROTEIN DIMER===
+[https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
-<!--
+Check<jmol>
-The line below this paragraph, {{ABSTRACT_PUBMED_7788292}}, adds the Publication Abstract to the page
+  <jmolCheckbox>
-(as it appears on PubMed at http://www.pubmed.gov), where 7788292 is the PubMed ID number.
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/1msc_consurf.spt"</scriptWhenChecked>
--->
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-{{ABSTRACT_PUBMED_7788292}}
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
-==About this Structure==
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1msc ConSurf].
-MSC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSC OCA].
+<div style="clear:both"></div>
+== References ==
-==Reference==
+<references/>
-Crystal structure of the MS2 coat protein dimer: implications for RNA binding and virus assembly., Ni CZ, Syed R, Kodandapani R, Wickersham J, Peabody DS, Ely KR, Structure. 1995 Mar 15;3(3):255-63. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7788292 7788292]
+__TOC__
-[[Category: Enterobacterio phage ms2]]
+</StructureSection>
-[[Category: Single protein]]
+[[Category: Escherichia phage MS2]]
-[[Category: Ely, K R.]]
+[[Category: Large Structures]]
-[[Category: Kodandapani, R.]]
+[[Category: Ely KR]]
-[[Category: Ni, C Z.]]
+[[Category: Kodandapani R]]
-[[Category: Translation repressor]]
+[[Category: Ni C-Z]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:05:08 2008''